… , fat metabolism, and glycemic control, multiple aspects of … ROS and cytokines subsequently
lead to MOF as well as … the ammonia enters the brain and crosses the blood-brain barrier.44 …

… affected organ systems followed by coagulation, brain, circulation and respiration. ACLF is
… For example, in the microvasculature of vital organs, proinflammatory cytokines damage the …

… a specific group of cytokines that play important roles in the pathogenesis of liver disease. In
… IL-17 regulation, signaling, and functions in the liver. Th17 cells differentiate from naive Th0 …

… of proinflammatory cytokines IL-6 and IL-1β from brain cells. In … fatty liver disease (MAFLD)
is a chronic liver disease that … slices from mice fed with CHOW diet serves as a control and …

… cellular network might regulate liver function and insulin … to discern the role of liver- vs adipose
tissue–derived cytokines in IR … brain function, neuroinflammation, and Alzheimer disease (…

… pathway regulates interferon regulatory factor leading to cytokine and interferon production.
In … All tissues (liver, brain, kidneys) were snap frozen in liquid nitrogen and stored at −80C for …

… release of proinflammatory cytokines, which drives cerebral edema and secondary organ …
with acute liver failure would clear the proinflammatory cytokines, bacterial endotoxin, …

… cytokines can alter insulin resistance in the liver and brain. Luteolin is detected in the brain
tissues after passing through the blood–brain … neuroinflammation and brain insulin resistance …

… These proinflammatory cytokines exacerbate neuronal damage, leading to brain dysfunction
in sepsis. Astrocytes also regulate the neuroinflammation during sepsis by controlling …

… In summary, in acute and chronic liver disease, ammonia … coupling, astrocytes tightly regulate
cerebral blood flow, and … was discovered, suggesting active cerebral cytokine production…