… less toxicity than autologous hematopoietic stem cell transplantation. An emerging field is to
… of regulatory T cells, which are dysfunctional in patients with systemic lupus erythematous, …

… P-selectin as a treatment for lupus Dysfunctional regulatory T (T reg ) cells are known to be
… pathogenesis of systemic lupus erythematosus (SLE), but the mechanisms mediating T reg …

… Systemic lupus erythematosus (SLE) is an autoimmune disease with multi-organ …
Impaired interleukin-2 (IL-2) production and dysfunction of regulatory T cells (Tregs) have been …

… for regulatory T cells (Treg cells), but recent studies have shown the plasticity and heterogeneity
of CD4 + Foxp3 + T cells. … + T cells in patients with systemic lupus erythematosus (SLE). …

… cells (TCR-β + CD44 lo CD62L hi ) (Figure 2C,D). Since cellular … T cells, we speculated
that activated T cells might have a stronger uptake capacity. To validate our hypothesis, T cells …

… of systemic lupus erythematosus (SLE), but follicular regulatory T (TFR) cells can potentially
suppress this abnormality. We investigate functional changes in TFR cells from SLE patients. …

… P2X7 receptor (P2X7R) is highly expressed on immune cells, triggering the release of … T
helper (Th) 1, Th17, and regulatory T (Treg) cells in patients with systemic lupus erythematosus (…

… Systemic lupus erythematosus (SLE) is associated with an IL-2–deficient state, with regulatory
T cells (Tregs) showing diminished immune regulatory capacity. A low dose of IL-2 has …

… , and follicular helper cells. SLE CD4 + T cells are known to provide help to B cells, produce
… In the absence of sufficient amounts of IL-2, regulatory T cells, do not function properly to …

… dysfunctional T-cell subsets over regulatory T cells is central to systemic lupus erythematosus
(… article discusses the function of T cells in SLE, primarily focusing on the various roles of T-…