Dopamine and dopamine-related ligands can bind not only to dopamine receptors
J Myslivecek - Life, 2022 - mdpi.com
The dopaminergic system is one of the most important neurotransmitter systems in the
central nervous system (CNS). It acts mainly by activation of the D1-like receptor family at the …
central nervous system (CNS). It acts mainly by activation of the D1-like receptor family at the …
Recent advances towards the discovery of dopamine receptor ligands
A Zhang, Y Kan, F Li - Expert Opinion On Therapeutic Patents, 2006 - Taylor & Francis
Dopamine is a key regulator in the CNS, contributing importantly to functions of arousal and
attention, initiation of movement, perception, motivation and emotion. Its imbalance has …
attention, initiation of movement, perception, motivation and emotion. Its imbalance has …
Current drug treatments targeting dopamine D3 receptor
Dopamine receptors (DR) have been extensively studied, but only in recent years they
became object of investigation to elucidate the specific role of different subtypes (D1R, D2R …
became object of investigation to elucidate the specific role of different subtypes (D1R, D2R …
Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds
Compounds that target D2-like dopamine receptors (DRs) are currently used as therapeutics
for several neuropsychiatric disorders including schizophrenia (antagonists) and …
for several neuropsychiatric disorders including schizophrenia (antagonists) and …
Targeting the receptor-based interactome of the dopamine D1 receptor: looking for heteromer-selective drugs
V Casadó-Anguera, A Cortés, V Casado… - Expert opinion on drug …, 2019 - Taylor & Francis
Introduction: G protein-coupled receptors (GPCRs) are a superfamily of membrane proteins
highly expressed in the brain that are involved in almost all functions of the CNS. During the …
highly expressed in the brain that are involved in almost all functions of the CNS. During the …
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases
D3 receptors represent a major focus of current drug design and development of
therapeutics for dopamine-related pathological states. Their close homology with the D2 …
therapeutics for dopamine-related pathological states. Their close homology with the D2 …
Dopamine receptor subtype-selective drugs: D2-like receptors
O Prante, M Dörfler, P Gmeiner - The dopamine receptors, 2010 - Springer
Drugs that are known to activate or block dopamine receptors are widely used for the
treatment of a number of severe diseases. In most cases, dopaminergic drugs preferentially …
treatment of a number of severe diseases. In most cases, dopaminergic drugs preferentially …
Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders
A Zhang, JL Neumeyer, RJ Baldessarini - Chemical reviews, 2007 - ACS Publications
Dopamine (DA) is a critical neurotransmitter in the mammalian central nervous system
(CNS). The cerebral dopaminergic system is implicated in the pathophysiology of several …
(CNS). The cerebral dopaminergic system is implicated in the pathophysiology of several …
Dopamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
JM Beaulieu, E Borrelli, A Carlsson… - IUPHAR/BPS guide to …, 2019 - journals.ed.ac.uk
Dopamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology
Database Page 1 IUPHAR/BPS Guide to Pharmacology CITE https://doi.org/10.2218/gtopdb/F20/2019.4 …
Database Page 1 IUPHAR/BPS Guide to Pharmacology CITE https://doi.org/10.2218/gtopdb/F20/2019.4 …
Dopamine D2 receptors dimers: how can we pharmacologically target them?
M Carli, S Kolachalam, S Aringhieri… - Current …, 2018 - ingentaconnect.com
Background: Dopamine D2 and D3 receptors can form homo-and heterodimers and are
important targets in Schizophrenia and Parkinson's. Recently, many efforts have been made …
important targets in Schizophrenia and Parkinson's. Recently, many efforts have been made …