Leptin, the product of the obesity gene, is a cytokine-like circulating protein acting as a
peripheral satiety signal to the hypothalamus. It was initially described as a secreted product …

Leptin is a mainly adipocyte-secreted protein that was discovered 5 years ago. Most of the
research following this discovery focused on the role of leptin in body weight regulation …

Leptin is a 16 kDa protein that exerts important effects on the regulation of food intake and
energy expenditure by interacting with the leptin receptor in the brain and in many other …

Although leptin was originally viewed as an antiobesity hormone, it is now evident that it may
have more pleiotropic actions. Experiments in rodents have shown that leptin activates the …

Leptin, the product of the obesity gene (ob) predominantly secreted from adipocytes, plays a
major role in the negative control of feeding and acts via a specific receptor (Ob‐R), six …

Leptin is a newly discovered hormone that acts as a feedback signal from the adipose
tissue. It plays a pivotal role in the modulation of neuronal and hormonal systems involved in …

Leptin is a peptide hormone released from adipose tissue and encoded by the obese (ob)
gene. While leptin's role is classically described in the regulation of appetite …

Leptin has received considerable attention as a newly recognized metabolic hormone and
for its potential for therapeutic use in the treatment of human obesity. Furthermore, defects in …

Leptin, a peptide hormone (167 aa) mainly expressed in adipocytes, and its hypothalamic
receptors are integral components of a complex physiological system evolved to regulate …

Leptin is an adipocyte hormone that signals nutritional status to the central nervous system
(CNS) and peripheral organs. Leptin is also synthetized in the placenta and in …