Argipressin for prevention of blood loss during liver resection: a study protocol for a randomised, placebo-controlled, double-blinded trial (ARG-01)

E Wisén, A Kvarnström, L Sand-Bown, M Rizell… - BMJ open, 2023 - bmjopen.bmj.com
Introduction Liver resection carries a high risk for extensive bleeding and need for blood
transfusions, which is associated with significant negative impact on outcome. In malignant …

[HTML][HTML] Protocol: Argipressin for prevention of blood loss during liver resection: a study protocol for a randomised, placebo-controlled, double-blinded trial (ARG-01)

E Wisén, A Kvarnström, L Sand-Bown, M Rizell… - BMJ Open, 2023 - ncbi.nlm.nih.gov
Introduction Liver resection carries a high risk for extensive bleeding and need for blood
transfusions, which is associated with significant negative impact on outcome. In malignant …

Efficacy and safety of terlipressin infusion during liver surgery: a protocol for systematic review and meta-analysis

L Ding, Y Duan, L Yao, Z Gao - BMJ open, 2024 - bmjopen.bmj.com
Introduction Liver disease causes 2 million deaths annually, accounting for 4% of all deaths
worldwide. Liver surgery is one of the effective therapeutic options. Bleeding is a major …

[HTML][HTML] Effectiveness of terlipressin for prevention of complications after major liver resection–a randomized placebo-controlled trial

A Kohler, S Perrodin, A De Gottardi, D Candinas… - HPB, 2020 - Elsevier
Background Elevated portal pressure in response to major liver resection is associated with
impaired liver regeneration and increased postoperative complications. Terlipressin, a …

Effects of terlipressin infusion on blood loss and transfusion needs during liver resection: a randomised trial

MS Abbas, KS Mohamed, OA Ibraheim… - Acta …, 2019 - Wiley Online Library
Background Blood loss and perioperative blood transfusion requirements affect the long‐
term survival after liver resection for malignant tumours. Terlipressin is a synthetic …

Effects of terlipressin infusion during hepatobiliary surgery on systemic and splanchnic haemodynamics, renal function and blood loss: a double-blind, randomized …

MM Mahdy, MS Abbas, EZ Kamel, MF Mostafa… - BMC …, 2019 - Springer
Background Terlipressin, in general, is a vasopressor which acts via V1 receptors. Its
infusion elevates mean blood pressure and can reduce bleeding which has a splanchnic …

[HTML][HTML] Desmopressin acetate decreases blood loss in patients with massive hemorrhage undergoing gastrointestinal surgery

LC Wang, YF Hu, L Chen, R Xing, XF Lin… - The Turkish Journal of …, 2020 - ncbi.nlm.nih.gov
Materials and Methods A multiple-center, double-blind clinical trial was conducted; patients
who underwent gastrointestinal surgery were recruited from three hospitals and were …

Desmopressin to reduce periprocedural bleeding and transfusion: a systematic review and meta-analysis

C Wang, V Lebedeva, J Yang, J Anih, LJ Park… - Perioperative …, 2024 - Springer
We systematically reviewed the literature to investigate the effects of peri-procedural
desmopressin in patients without known inherited bleeding disorders undergoing surgery or …

Tranexamic acid versus placebo to reduce perioperative blood transfusion in patients undergoing liver resection: protocol for the haemorrhage during liver resection …

PJ Karanicolas, Y Lin, S McCluskey, R Roke… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Despite use of operative and non-operative interventions to reduce blood loss
during liver resection, 20%–40% of patients receive a perioperative blood transfusion …

Pharmacological interventions for ischaemia reperfusion injury in liver resection surgery performed under vascular control

M Abu‐Amara, KS Gurusamy… - Cochrane Database …, 1996 - cochranelibrary.com
Background Vascular occlusion used during elective liver resection to reduce blood loss
results in significant ischaemia reperfusion (IR) injury. This in turn leads to significant …