Vascular endothelial growth factor-D (VEGF-D): An angiogenesis bypass in malignant tumors

SMZ Bokhari, P Hamar - International Journal of Molecular Sciences, 2023 - mdpi.com
Vascular endothelial growth factors (VEGFs) are the key regulators of vasculogenesis in
normal and oncological development. VEGF-A is the most studied angiogenic factor …

The critical role of vascular endothelial growth factor in tumor angiogenesis

A Amini, S Masoumi Moghaddam… - Current cancer drug …, 2012 - ingentaconnect.com
Angiogenesis is the formation of new blood vessels from the pre-existing vasculature.
Besides its role in normal physiology, angiogenesis is significantly involved in many …

Pivotal role of vascular endothelial growth factor pathway in tumor angiogenesis

SH Lee, D Jeong, YS Han… - Annals of surgical …, 2015 - synapse.koreamed.org
The shaping of new blood vessels is a significant event in cancer growth and metastasis.
Therefore, the molecular system of cancer angiogenesis has garnered considerable interest …

Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis

DJ Hicklin, LM Ellis - Journal of clinical oncology, 2005 - ascopubs.org
New blood vessel formation (angiogenesis) is a fundamental event in the process of tumor
growth and metastatic dissemination. Hence, the molecular basis of tumor angiogenesis has …

Vascular endothelial growth factor-D: signaling mechanisms, biology, and clinical relevance

MG Achen, SA Stacker - Growth Factors, 2012 - Taylor & Francis
Vascular endothelial growth factor-D (VEGF-D) is a secreted glycoprotein that promotes
growth of blood vessels (angiogenesis) and lymphatic vessels (lymphangiogenesis), and …

The angiogenic and lymphangiogenic factor vascular endothelial growth factor-D exhibits a paracrine mode of action in cancer

MG Achen, RA Williams, ME Baldwin, P Lai… - Growth …, 2002 - Taylor & Francis
Vascular endothelial growth factor-D (VEGF-D) promotes angiogenesis, lymphangiogenesis
and metastatic spread via the lymphatics, however, the mode of VEGF-D action (eg …

VEGF as a key mediator of angiogenesis in cancer

P Carmeliet - Oncology, 2005 - karger.com
Vascular endothelial growth factor (VEGF) is a homodimeric glycoprotein with a molecular
weight of approximately 45 kDa. It is the key mediator of angiogenesis (the formation of new …

[图书][B] VEGF and Cancer

JH Harmey - 2004 - books.google.com
VEGF and Canceris a comprehensive and up to date review of current knowledge on the
role of vascular endothelial growth factor (VEGF) in cancer. Key Features:-Discussion of …

Vascular endothelial growth factor (VEGF) signaling in tumour vascularization: potential and challenges

K Sivaraman Siveen, K Prabhu… - Current vascular …, 2017 - ingentaconnect.com
Angiogenesis is defined as the physiological process by which new blood vessels develop
from pre-existing vessels; either by sprouting or intussusception. Inhibition of angiogenesis …

Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF)

AM Byrne, DJ Bouchier‐Hayes… - Journal of cellular and …, 2005 - Wiley Online Library
Vascular endothelial growth factor (VEGF) was originally identified as an endothelial cell
specific growth factor stimulating angiogenesis and vascular permeability. Some family …