Effects of Endotoxin Tolerance Induced by Porphyromonas gingivalis Lipopolysaccharide on Inflammatory Responses in Neutrophils

J Gu, Y Liu, X Zhu, J Qiu, Y Sun - Inflammation, 2020 - Springer
Periodontitis is a dental plaque–induced chronic inflammatory disease. Long-term exposure
of the host to periodontal pathogens leads to a hyporesponsive state to the following …

[HTML][HTML] Effects of Porphyromonas gingivalis LipopolysaccharideTolerized Monocytes on Inflammatory Responses in Neutrophils

X Zhu, W Lu, Y Chen, X Cheng, J Qiu, Y Xu, Y Sun - PLoS One, 2016 - journals.plos.org
Periodontitis is a chronic inflammatory disease induced by bacteria. Exposure of the host to
periodontal pathogens and their virulence factors induces a state of hyporesponsiveness to …

Endotoxin tolerance induced by Porphyromonas gingivalis lipopolysaccharide alters macrophage polarization

JY Gu, Z Fu, JL Chen, YJ Liu, X Cao, Y Sun - Microbial pathogenesis, 2022 - Elsevier
Endotoxin tolerance refers to a state refractory to subsequent lipopolysaccharide (LPS)
stimulations following a primary LPS exposure. To study the relationship between endotoxin …

Impaired Immune Tolerance to Porphyromonas gingivalis Lipopolysaccharide Promotes Neutrophil Migration and Decreased Apoptosis

S Zaric, C Shelburne, R Darveau, DJ Quinn… - Infection and …, 2010 - Am Soc Microbiol
Periodontitis, a chronic inflammatory disease of the tissues supporting the teeth, is
characterized by an exaggerated host immune and inflammatory response to …

[HTML][HTML] Excessive neutrophil extracellular trap formation induced by Porphyromonas gingivalis lipopolysaccharide exacerbates inflammatory responses in high …

Y Tong, Y Xin, L Fu, J Shi, Y Sun - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Introduction Neutrophil extracellular trap (NET) is a novel defense strategy of neutrophils
and found to be induced by Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide …

Immunological response of human leucocytes after exposure to lipopolysaccharides from Porphyromonas gingivalis

S Alizadehgharib, AK Östberg… - Clinical and …, 2021 - Wiley Online Library
Porphyromonas gingivalis (P. gingivalis) is a gram‐negative bacterium and an important
etiologic agent of periodontitis. P. gingivalis releases outer membrane vesicles containing …

Endotoxin Tolerance Induced by Lipopolysaccharides Derived from Porphyromonas gingivalis and Escherichia coli: Alternations in Toll-Like Receptor 2 and 4 …

Y Sun, H Li, MJ Sun, YY Zheng, DJ Gong, Y Xu - Inflammation, 2014 - Springer
Periodontitis is a chronic inflammatory disease induced by bacteria. Exposure of the host to
periodontal pathogens and their virulence factors induces a hyporesponsive state to …

Neutrophil extracellular traps induced by Porphyromonas gingivalis lipopolysaccharide modulate inflammatory responses via a Ca2+-dependent pathway

J Chen, Y Tong, Q Zhu, L Gao, Y Sun - Archives of Oral Biology, 2022 - Elsevier
Objective The aim of this study was to explore the effects and underlying mechanisms of
Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide (LPS) on the formation of …

[HTML][HTML] Effects of Aging on Endotoxin Tolerance Induced by Lipopolysaccharides Derived from Porphyromonas gingivalis and Escherichia coli

Y Sun, H Li, MF Yang, W Shu, MJ Sun, Y Xu - PLoS one, 2012 - journals.plos.org
Background Periodontitis is a bacterially induced chronic inflammatory disease. Exposure of
the host to periodontal pathogens and their virulence factors induces a state of …

[HTML][HTML] Application of the in vitro HOXB8 model system to characterize the contributions of neutrophil–lps interaction to periodontal disease

M Sochalska, MB Stańczyk, M Użarowska, N Zubrzycka… - Pathogens, 2020 - mdpi.com
(1) Background: Studying neutrophils in vitro is difficult since these cells are terminally
differentiated and are easily activated during isolation. At the same time, most of the …