Ammonia exposure impairs lateral-line hair cells and mechanotransduction in zebrafish embryos

LY Lin, JA Zheng, SC Huang, GY Hung, JL Horng - Chemosphere, 2020 - Elsevier
Ammonia (including NH 3 and NH 4+) is a major pollutant of freshwater environments.
However, the toxic effects of ammonia on the early stages of fish are not fully understood …

Acidified water impairs the lateral line system of zebrafish embryos

LY Lin, GY Hung, YH Yeh, SW Chen, JL Horng - Aquatic toxicology, 2019 - Elsevier
Acidification of freshwater ecosystems is recognized as a global environmental problem.
However, the influence of acidic water on the early stages of freshwater fish is still unclear …

Ammonia excretion by the skin of zebrafish (Danio rerio) larvae

TH Shih, JL Horng, PP Hwang… - American Journal of …, 2008 - journals.physiology.org
The mechanism of ammonia excretion in freshwater teleosts is not well understood. In this
study, scanning ion-selective electrode technique was applied to measure H+ and NH4+ …

Nitrogenous Waste Handling by Larval Zebrafish Danio rerio in Alkaline Water

Y Kumai, J Harris, H Al-Rewashdy… - Physiological and …, 2015 - journals.uchicago.edu
Although adult fish excrete their nitrogenous waste primarily as ammonia, larval fish may
excrete a higher proportion as urea, an evolutionary strategy that lessens nitrogenous waste …

High dissolved oxygen exacerbates ammonia toxicity with sex-dependent manner in zebrafish

SX Sun, CT Hu, F Qiao, LQ Chen, ML Zhang… - … and Physiology Part C …, 2023 - Elsevier
Ammonia nitrogen is one of the important environmental factors, and causes negative effects
for fish health in ecosystem and aquaculture. The toxic effects and mechanisms of ammonia …

Extracellular Ca2+ and Mg2+ modulate aminoglycoside blockade of mechanotransducer channel-mediated Ca2+ entry in zebrafish hair cells: an in vivo study with …

LY Lin, W Pang, WM Chuang… - … of Physiology-Cell …, 2013 - journals.physiology.org
Zebrafish lateral-line hair cells are an in vivo model for studying hair cell development,
function, and ototoxicity. However, the molecular identification and properties of the …

Rhcg1 and NHE3b are involved in ammonium-dependent sodium uptake by zebrafish larvae acclimated to low-sodium water

TH Shih, JL Horng, ST Liu… - American Journal of …, 2012 - journals.physiology.org
To investigate whether Na+ uptake by zebrafish is dependent on NH4+ excretion, a
scanning ion-selective electrode technique was applied to measure Na+ and NH4+ …

Exposure to sodium metam during zebrafish somitogenesis results in early transcriptional indicators of the ensuing neuronal and muscular dysfunction

F Tilton, RL Tanguay - Toxicological sciences, 2008 - academic.oup.com
Exposures to sodium metam (NaM) within the developmental period of somitogenesis (10-to
18-h postfertilization [hpf]) results in easily detectable distortions of the notochord by 24 hpf …

Transcriptomic analysis reveals different responses to ammonia stress and subsequent recovery between Coilia nasus larvae and juveniles

J Gao, Y Zhu, Z Guo, G Xu, P Xu - … and Physiology Part C: Toxicology & …, 2020 - Elsevier
Excessive ammonia triggered negative effects on aquatic animals' health, growth, and mass
death, especially at different developmental periods. However, the underlying responses to …

The sensory-motor responses to environmental acidosis in larval zebrafish: Influences of neurotransmitter and water chemistry

R JavadiEsfahani, RWM Kwong - Chemosphere, 2019 - Elsevier
The sensory-motor function in larval zebrafish (Danio rerio) following exposure to low water
pH was investigated. The results suggested that acid exposure (pH 4.0–5.0; control: pH 7.4) …