Coronary artery bypass grafting (CABG) induces pro-inflammatory and immunomodulatory phenotype of platelets in the absence of a pro-aggregatory state

E Hosseini, J Ahmadi, F Kargar… - Microvascular Research, 2024 - Elsevier
Background Coronary artery bypass grafting (CABG) is considered a choice treatment for
patients suffering from coronary artery disease (CAD). In the inflammatory milieu of …

[HTML][HTML] Coronary artery bypass graft surgery up‐regulates genes involved in platelet aggregation

SJ REILLY, N Li, J Liska, M Ekström… - Journal of Thrombosis and …, 2012 - Elsevier
Background: During and shortly after coronary artery bypass graft (CABG) surgery, there is
an increase in thromboembolic events. CABG, a strong inflammatory stimulus, is associated …

[HTML][HTML] Biphasic pro-thrombotic and inflammatory responses after coronary artery bypass surgery

N Li, R Astudillo, T Ivert, P Hjemdahl - Journal of Thrombosis and …, 2003 - Elsevier
Early graft failure after coronary artery bypass grafting (CABG) is related to thrombosis and
inflammation in the grafted vessel (s). The time courses of, and relationships between, pro …

Increased platelet reactivity and platelet–leukocyte aggregation after elective coronary bypass surgery

T Ivert, M Dalén, C Ander, R Stålesen, M Lordkipanidzé… - Platelets, 2019 - Taylor & Francis
Inflammatory mechanisms are activated, and thrombotic complications occur during the
initial months after coronary artery bypass grafting (CABG). Therefore, changes over time of …

Platelet activation and cytokine production during hypothermic cardiopulmonary bypass–a possible correlation?

P Ferroni, G Speziale, G Ruvolo… - Thrombosis and …, 1998 - thieme-connect.com
Cardiopulmonary bypass (CPB) is associated with impaired platelet function and a systemic
inflammatory response. The present study was designed to evaluate whether any correlation …

[图书][B] Cytokine responses and anti-inflammatory strategies in Coronary Artery Bypass Grafting

M Wei - 2001 - trepo.tuni.fi
It is well established that conventional coronary artery bypass grafting with cardiopulmonary
bypass induces a systemic inflammatory response, but the mechanism involved is still less …

Platelet activity before and after coronary artery bypass grafting

G Kobzar, V Mardla, I Rätsep, N Samel - Platelets, 2006 - Taylor & Francis
The normal response of the platelet can be altered either by increased pro-aggregatory
stimuli or by diminished anti-aggregatory substances. Increased platelet activation occurs in …

Inflammatory response and platelet activation after off-pump coronary artery bypass surgery

O Aljassim, M Karlsson, L Wiklund… - Scandinavian …, 2006 - Taylor & Francis
Background. Cardiac surgery induces a systemic inflammatory activation and alterations in
the hemostatic cascade. The responses contribute to postoperative complications but may …

THROMBOINFLAMMATORY RESPONSE TO ON-PUMP CORONARY ARTERY BYPASS GRAFT SURGERY LEADS TO IMPAIRED PLATELET REACTIVITY IN …

N Elamin, T Nelson, W Parker, F Varian… - Journal of the American …, 2022 - jacc.org
Background Patients with acute coronary syndrome (ACS) undergoing coronary artery
bypass graft (CABG) are at risk of bleeding despite stopping ticagrelor days before. The …

[HTML][HTML] Comparison of inflammatory response following coronary revascularization with or without cardiopulmonary bypass

B Gasz, L Benkö, G Jancsó, J Lantos… - … & Clinical Cardiology, 2004 - ncbi.nlm.nih.gov
BACKGROUND: It is well known that conventional coronary revascularization is associated
with a pronounced systemic inflammatory response due to the application of …