Myeloid ecotropic virus insertion site 1 (MEIS1) is a HOX co-factor necessary for organ
development and normal hematopoiesis. Recently, MEIS1 has been linked to the …

Neuroblastoma is one of only a few human cancers that can spontaneously regress even
after extensive dissemination, a poorly understood phenomenon that occurs in as many as …

The three amino acid loop extension (TALE) class myeloid ecotropic viral integration site 1
(MEIS1) homeobox gene is known to play a crucial role in normal and tumor development …

MEIS1 (Myeloid ecotropic viral integration site 1) is a homeodomain transcription factor that
cooperates with Hox family proteins in both normal and leukemic hematopoiesis. 1 MEIS1 is …

We recently found amplification of the TALE homeobox gene MEIS1 in the IMR32
neuroblastoma cell line. We now demonstrate high-level expression of the MEIS1 and …

Simple Summary Glioblastoma is the most common and lethal primary brain tumor for which
no curative treatment currently exists. In our previous work, we showed that MEOX2 was …

Background MEIS1 (Myeloid ecotropic viral integration site 1) as a homeobox (HOX)
transcription factor plays regulatory roles in a variety of cellular processes including …

Background MEIS1 (Myeloid ecotropic viral integration site 1), as a homeobox (HOX)
transcription factor, has a dual function in different types of cancer. Although numerous roles …

Central nervous system development is controlled by highly conserved homeoprotein
transcription factors including HOX and TALE (Three Amino acid Loop E xtension). TALE …

Background Glioblastoma (GBM) is the most lethal brain tumor characterized by high
morbidity and limited treatment options. Tumor malignancy is usually associated with the …