Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disorder.
Kidney involvement, termed lupus nephritis (LN), is seen in 40–60% of patients with …

Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease that can affect
any organ of the body. Multiple mechanisms may contribute to the pathophysiology of …

Patients with systemic lupus erythematosus frequently develop lupus nephritis (LN), a
condition that can lead to end-stage kidney disease. Multiple serum and urine biomarkers …

Although biomarkers have high utility for the diagnosis of systemic lupus erythematosus
(SLE), current serologic and urinary markers do not correlate well with nephritic activity. This …

Objective Lupus nephritis (LN) is diagnosed by biopsy, but longitudinal monitoring
assessment methods are needed. Here, in this preliminary and hypothesis-generating study …

There has long been a need for biomarkers of disease activity in lupus nephritis (LN). Such
markers ideally would be capable of detecting early sub-clinical disease and could be used …

Renal involvement in patients with systemic lupus erythematosus in the form of severe lupus
nephritis is associated with a significant burden of morbidity and mortality. Conventional …

Kidney disease is one of the most serious manifestations of systemic lupus erythematosus
(SLE). Despite the improvement in the medical care of SLE in the past two decades, the …

Introduction One third of lupus nephritis (LN) patients develop irreversible kidney damage
despite achieving a clinical response based on resolution of proteinuria. Furthermore, per …

Objectives. Key aims of the treatment of lupus nephritis (LN) are to induce and maintain
remission with minimal side effects. However, assessing ongoing renal inflammatory activity …