OBJECTIVE The Multidomain Alzheimer Preventive Trial (MAPT study) was designed to
assess the efficacy of isolated supplementation with omega-3 fatty acid, an isolated …

BACKGROUND: Because no effective curative approaches are available, preventive
approaches in the field of Alzheimer's disease (AD) are needed. We present the design of …

Findings from recent Alzheimer's disease prevention trials have shown subjects with
increased dementia score based upon mid-life cardiovascular risk factors, to benefit from …

Background No large trials have been done to investigate the efficacy of an intervention
combining a specific compound and several lifestyle interventions compared with placebo …

Alzheimer's disease (AD) is the leading cause of dementia and the most common
neurodegenerative disease in the elderly. Furthermore, AD has provided the most positive …

Preventing or postponing the onset of Alzheimer's disease (AD) and delaying or slowing its
progression would lead to a consequent improvement of health status and quality of life in …

Oxidative stress, inflammation, and increased cholesterol levels are all mechanisms that
have been associated with Alzheimer's disease (AD) pathology. Several epidemiologic …

Introduction: Alzheimer's disease (AD) is a neurodegeneration disorder characterized by
progressive impairments of memory, language, reasoning, and other cognitive functions …

Previous data have linked omega-3 fatty acids with risk of dementia. We aimed to assess the
longitudinal relationships of omega-3 polyunsaturated fatty acid intake as well as blood …

Alzheimer's disease (AD) is the most common form of dementia. AD initially targets memory
and progressively destroys the mind. The brain atrophies as the neocortex suffers neuronal …