Clasmatodendrosis derives from the Greek for fragment (klasma), tree (dendron), and
condition (-osis). Cajal first used the term in 1913: he observed disintegration of the distal …

Mechanisms by which astrocytes are irreversibly injured from ischemic brain injury remain
incompletely defined. More than 90 years ago Alzheimer showed that astrocytes lose their …

Objectives: To present the incidence of clasmatodendrosis (injured astrocytic processes)
and analyse the association between clasmatodendrosis and the ubiquitin proteasome …

The pathogenesis of white matter lesions, which are frequently found in ischemic
cerebrovascular disease and Alzheimer's disease, remains unclear. Using light and electron …

Brain injury causes astrocytes to become reactive (astrogliosis). In this study, we compared
astrogliosis in acutely injured cortex and striatum of adult FVB/N mice induced by stereotaxic …

White matter hyperintensities as seen on brain T 2-weighted magnetic resonance imaging
are associated with varying degrees of cognitive dysfunction in stroke, cerebral small vessel …

Angiogenesis plays a pivotal role in the physiology and pathology of the brain.
Microvascular alterations have been observed in various neurodegenerative disorders …

CADASIL (Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy) is a type of small‐artery stroke and vascular dementia‐inducing …

Electron microscopical examination of devastated and reticular gliosis-replaced areas of two
human brains revealed novel anchorage densities (ADs) associated with hemidesmosome …

Diaschisis has been described as functional depression distant to the lesion. A variety of
neuroscientific approaches have been used to investigate the mechanisms underlying …