Systematic review and meta-analysis of randomized controlled trials on safety and effectiveness of oral anticoagulants for atrial fibrillation in older people

G Erdem, M Esme, BB Doğu - Irish Journal of Medical Science (1971-), 2022 - Springer
A meta-analysis of prospective, randomized controlled trials on novel oral anticoagulants
(NOACs) versus warfarin, as most commonly used vitamin K antagonists (VKAs), was done …

New oral anticoagulants for nonvalvular atrial fibrillation in the elderly: limited applicability in primary care

W Opstelten, M van den Donk, T Kuijpers… - European Journal of …, 2015 - Taylor & Francis
Background: Based on the results from randomized controlled trials (RCTs), new oral
anticoagulants (NOACs) seem attractive alternatives to vitamin K antagonists (VKAs) …

Effectiveness and safety of oral anticoagulants in older patients with atrial fibrillation: a systematic review and meta-regression analysis

Y Bai, SD Guo, H Deng, A Shantsila, L Fauchier… - Age and …, 2018 - academic.oup.com
Background and objective the study analysed the effectiveness and safety of warfarin use
compared with warfarin non-use and non-vitamin K antagonist oral anticoagulants (NOACs) …

[HTML][HTML] Treating atrial fibrillation in very old patients with new oral anticoagulation drugs: arguments pro and contra

MD Toader - Europian Journal of Cardiology Practice, 2019 - escardio.org
Stroke prevention in very old patients with atrial fibrillation remains a challenge. There is a
high risk of systemic thromboembolism but also a high risk of bleeding if anticoagulants are …

Efficacy and Safety of Oral Anticoagulants in Older Adult Patients with Atrial Fibrillation: Pairwise and Network Meta-Analyses

X Wang, T Wang, X Chen, W Tian, D Ma… - Journal of the American …, 2023 - Elsevier
Objective To evaluate the efficacy and safety of oral anticoagulants for older adult patients
with atrial fibrillation (AF). Design Pairwise and network meta-analyses. Setting and …

Outcome of novel oral anticoagulant versus warfarin in frail elderly patients with atrial fibrillation: a systematic review and meta-analysis of retrospective studies

J Hu, Y Zhou, Z Cai - Acta Clinica Belgica, 2023 - Taylor & Francis
Background Frail patients with atrial fibrillation (AF) are thought to be at a higher risk for
cerebral infarction and death than patients who are not frail, making preventive interventions …

Safety and efficacy of non-vitamin K antagonist oral anticoagulants in elderly patients with atrial fibrillation: systematic review and meta-analysis of 22 studies and 440 …

A Silverio, M Di Maio, C Prota… - European Heart …, 2021 - academic.oup.com
Aims The aim of the present meta-analysis was to evaluate the efficacy and safety of non-
vitamin K oral antagonists (NOACs) vs. vitamin K antagonists (VKAs) in elderly patients with …

Effectiveness and safety of direct oral anticoagulants versus vitamin K antagonists for people aged 75 years and over with atrial fibrillation: a systematic review and …

A Mitchell, MC Watson, T Welsh… - Journal of clinical medicine, 2019 - mdpi.com
Older people, are underrepresented in randomised controlled trials of direct oral
anticoagulants (DOACs) for stroke prevention in atrial fibrillation (AF). The aim of this study …

[PDF][PDF] Efficacy and safety of oral anticoagulation in elderly patients with atrial fibrillation.

I Cavallari, G Patti - Anatolian Journal of Cardiology/Anadolu …, 2018 - jag.journalagent.com
Elderly patients with atrial fibrillation are at a higher risk of both ischemic and bleeding
events compared with younger patients; therefore, balancing risks and benefits of …

Oral anticoagulation in very elderly patients with atrial fibrillation: a nationwide cohort study

TF Chao, CJ Liu, YJ Lin, SL Chang, LW Lo, YF Hu… - Circulation, 2018 - Am Heart Assoc
Background: Stroke prevention with oral anticoagulants (OACs) is the cornerstone for the
management of atrial fibrillation (AF). However, data about the use of OACs among …