The raphe nuclei comprise nearly all of 5-hydroxytryptaminergic (5-HTergic) neurons in the
brain and are widely acknowledged to participate in the modulation of neural …

Aims Epilepsy, frequently comorbid with depression, easily develops drug resistance. Here,
we investigated how dorsal raphe (DR) and its 5‐HTergic neurons are implicated in …

Generalized epilepsy affects 24 million people globally; at least 25% of cases remain
medically refractory. The thalamus, with widespread connections throughout the brain, plays …

The raphe nuclei, the primary resource of forebrain 5-HT, play an important but
heterogeneous role in regulating subcortical excitabilities. Fundamental circuit organizations …

The dorsal raphe nucleus (DRN) is the origin of the central serotonin [5-hydroxytryptamine
(5-HT)] system and plays an important role in the regulation of many physiological functions …

We studied electrophysiological properties, synaptic transmission and modulation by 5‐
hydroxytryptamine (5‐HT) of caudal raphe neurons using whole‐cell recording in a neonatal …

Absence epilepsy is the most common type of epilepsy in childhood (Glauser et al., 2010). It
is characterized by sudden, transient loss of consciousness, behavioral arrest, and an EEG …

Serotonin and SUDEP serotonin, while the raphe obscurus and raphe pallidus have
extensive descending projections to brainstem and spinal cord. In the context of epilepsy …

The dorsal (DR) and median raphe (MR) nuclei contain 5-hydroxytryptamine (serotonin, 5-
HT) cell bodies that give rise to the majority of the ascending 5-HT projections to the …

Epilepsy represents a condition in which abnormal neuronal discharges or the
hyperexcitability of neurons occur with synchronicity, presenting a significant public health …