Patient-reported outcomes in randomized controlled trials of patients with multiple myeloma: a systematic literature review of studies published between 2014 and …

F Efficace, F Cottone, F Sparano, G Caocci… - … Myeloma and Leukemia, 2022 - Elsevier
Background We performed a systematic literature review to identify the most recently
published randomized controlled trials (RCTs) in multiple myeloma (MM) with a patient …

[HTML][HTML] Interpreting clinical trial data in multiple myeloma: translating findings to the real-world setting

PG Richardson, JF San Miguel, P Moreau… - Blood cancer …, 2018 - nature.com
Substantial improvements in survival have been seen in multiple myeloma (MM) over recent
years, associated with the introduction and widespread use of multiple novel agents and …

[HTML][HTML] Guidelines for the Use and Reporting of Patient-Reported Outcomes in Multiple Myeloma Clinical Trials

E Laane, S Salek, EN Oliva, C Bennink, S Clavreul… - Cancers, 2023 - mdpi.com
Simple Summary It is recognized that patients with multiple myeloma (MM) experience a
high burden of disease and treatment-related symptoms that impact upon their quality of life …

[HTML][HTML] The reporting, use, and validity of patient-reported outcomes in multiple myeloma in clinical trials: a systematic literature review

S Salek, T Ionova, EN Oliva, M Andreas, N Skoetz… - Cancers, 2022 - mdpi.com
Simple Summary In multiple myeloma, a type of blood cancer, the measurement of the
outcomes of treatment reported by patients (patient-reported outcome measurement) is …

[HTML][HTML] Real-world and clinical trial data in relapsed/refractory multiple myeloma (RRMM): evaluating treatment duration and comparing effectiveness and efficacy

PG Richardson, JF San Miguel, P Moreau, R Hajek… - Blood, 2017 - Elsevier
Background The introduction of novel agents has contributed to improvements in survival in
multiple myeloma (MM), and, based on phase 3 investigations, multiple novel regimens …

Patient-reported outcomes in relapsed/refractory multiple myeloma: a systematic review

F Sparano, M Cavo, P Niscola, T Caravita… - Supportive Care in …, 2018 - Springer
Purpose We performed a systematic review to quantify the amount of evidence-based data
available on patient-reported outcomes (PRO) in Relapsed/Refractory Multiple Myeloma …

Attrition and withdrawal in multiple myeloma randomized controlled trials: A systematic review

S Hentzen, T Meirson, K Koehn… - European Journal of …, 2023 - Wiley Online Library
Objectives Patients with multiple myeloma (MM) enrolled in randomized control trials (RCTs)
discontinue treatment for various reasons; however, no prior study has analyzed reasons for …

Refractoriness to last line of therapy: how often is it mandated and reported? A systematic review of randomized myeloma trials

P Bindal, M Najjar, K Koehn, A Godara… - Leukemia & …, 2023 - Taylor & Francis
Poorva Bindal a, Mimi Najjar b, Kelly Koehn c, Amandeep Godara d, douglas W Sborov d,
Brian McClune d, Kelley Jullian d, Charlotte Wagner d and Ghulam rehman Mohyuddin d …

Patient-reported outcomes in clinical trials for multiple myeloma: Where we are.

M Andreas, S Salek, N Kreuzberger, V Piechotta… - 2021 - ascopubs.org
e18615 Background: It is recommended to include patient-reported outcomes (PROs) in
cancer trials to ensure clinical benefit based on patients' perceptions. For multiple myeloma …

Reporting of postprotocol therapies and attrition in multiple myeloma randomized clinical trials: a systematic review

GR Mohyuddin, K Koehn, AO Abdallah… - JAMA Network …, 2021 - jamanetwork.com
Importance A thorough understanding of the optimal role and sequence of agents for
treatment of multiple myeloma (MM) requires knowledge of the use and rate of postprotocol …