Noninvasive quantification of heterogeneous lung growth following extensive lung resection by high-resolution computed tomography

C Yilmaz, P Ravikumar, DM Dane… - Journal of applied …, 2009 - journals.physiology.org
To quantify the in vivo magnitude and distribution of regional compensatory lung growth
following extensive lung resection, we performed high-resolution computed tomography at …

Progressive adaptation in regional parenchyma mechanics following extensive lung resection assessed by functional computed tomography

C Yilmaz, NJ Tustison, DM Dane… - Journal of applied …, 2011 - journals.physiology.org
In adult canines following major lung resection, the remaining lobes expand asymmetrically,
associated with alveolar tissue regrowth, remodeling, and progressive functional …

Defining a stimuli-response relationship in compensatory lung growth following major resection

P Ravikumar, C Yilmaz, DM Dane… - Journal of applied …, 2014 - journals.physiology.org
Major lung resection is a robust model that mimics the consequences of loss-of-functioning
lung units. We previously observed in adult canines, following 42% and 58% lung resection …

Regional lung growth following pneumonectomy assessed by computed tomography

P Ravikumar, C Yilmaz, DM Dane… - Journal of applied …, 2004 - journals.physiology.org
After pneumonectomy (PNX), mechanical strain on the remaining lung is greatly increased.
To assess whether remaining lobes expand uniformly after left or right PNX (removing 42 …

Quantitative morphology of compensatory lung growth

CCW Hsia - European Respiratory Review, 2006 - Eur Respiratory Soc
Compensatory lung growth is defined by the absolute increases in the quantity of functioning
lung tissue in response to injury and/or disease, leading to a positive impact on functional …

Regional lung expansion at total lung capacity in intact vs. excised canine lungs

PA Chevalier, JR Rodarte… - Journal of Applied …, 1978 - journals.physiology.org
A computer-based biplane videoroentgenographic recording technique that determines the
spatial coordinates of radiopaque lung parenchymal markers was used to compare regional …

Developmental signals do not further accentuate nonuniform postpneumonectomy compensatory lung growth

P Ravikumar, C Yilmaz, DM Dane… - Journal of applied …, 2007 - journals.physiology.org
Mechanical forces imposed on lung tissue constitute major stimuli for normal lung
development and postpneumonectomy (PNX) compensatory growth and remodeling …

Shifting sources of functional limitation following extensive (70%) lung resection

CCW Hsia, DM Dane, AS Estrera… - Journal of applied …, 2008 - journals.physiology.org
We previously found that, following surgical resection of∼ 58% of lung units by right
pneumonectomy (PNX) in adult canines, oxygen-diffusing capacity (DlO2) fell sufficiently to …

Effect of body orientation on regional lung expansion: a computed tomographic approach

EA Hoffman - Journal of Applied Physiology, 1985 - journals.physiology.org
The Dynamic Spatial Reconstructor (DSR) was used to study in vivo lung geometry and
function. By replacing the lungs of three dogs with potato flakes and ping-pong balls of …

Lung volumes before and after lung volume reduction surgery: quantitative CT analysis

MD Becker, YM Berkmen, JHM Austin… - American journal of …, 1998 - atsjournals.org
The volume and severity of pulmonary emphysema in individual lungs were measured by
means of quantitative computed tomography (CT) studies in 28 patients (14 women, 14 men …