[HTML][HTML] Genomics of Trypanosomatidae: where we stand and what needs to be done?

V Yurchenko, A Butenko, AY Kostygov - Pathogens, 2021 - mdpi.com
Trypanosomatids are easy to cultivate and they are (in many cases) amenable to genetic
manipulation. Genome sequencing has become a standard tool routinely used in the study …

Functional genomics of trypanosomatids

J Choi, NM El‐Sayed - Parasite immunology, 2012 - Wiley Online Library
The decoding of the Tritryp reference genomes nearly 7 years ago provided a first peek into
the biology of pathogenic trypanosomatids and a blueprint that has paved the way for …

Genome evolution in trypanosomatid parasites

AP Jackson - Parasitology, 2015 - cambridge.org
A decade of genome sequencing has transformed our understanding of how trypanosomatid
parasites have evolved and provided fresh impetus to explaining the origins of parasitism in …

[HTML][HTML] Trypanosomatid comparative genomics: contributions to the study of parasite biology and different parasitic diseases

SM Teixeira, RMC Paiva… - … and molecular biology, 2012 - SciELO Brasil
In 2005, draft sequences of the genomes of Trypanosoma brucei, Trypanosoma cruzi and
Leishmania major, also known as the Tri-Tryp genomes, were published. These protozoan …

Trypanosomatid biology and euglenozoan evolution: new insights and shifting paradigms revealed through genome sequencing

ML Ginger - Protist, 2005 - Elsevier
Some of the biochemical peculiarities that occur in trypanosomatid protozoa are relatively
well known: compartmentalisation of glycolytic enzymes within microbodies of the …

[HTML][HTML] Shining the spotlight on the neglected: new high-quality genome assemblies as a gateway to understanding the evolution of Trypanosomatidae

ATS Albanaz, M Carrington, AO Frolov, AI Ganyukova… - BMC genomics, 2023 - Springer
Background Protists of the family Trypanosomatidae (phylum Euglenozoa) have gained
notoriety as parasites affecting humans, domestic animals, and agricultural plants. However …

Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution

DA Maslov, FR Opperdoes, AY Kostygov, H Hashimi… - Parasitology, 2019 - cambridge.org
Unicellular flagellates of the family Trypanosomatidae are obligatory parasites of
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …

Status of protozoan genome analysis: trypanosomatids

JM Blackwell, SE Melville - Parasitology, 1999 - cambridge.org
The three trypanosomatid genome projects have employed common strategies which
include: analysis of pulsed-field gel electrophoretic chromosomal karyotypes; physical …

Trypanosomatid genome organization and ploidy

JL Reis-Cunha, HO Valdivia… - Frontiers in …, 2017 - books.google.com
In 2005, the draft genome sequences of the parasites Trypanosoma cruzi, Trypanosoma
brucei and Leishmania major, also known as the Tritryps, were published providing major …

Protozomics: trypanosomatid parasite genetics comes of age

SM Beverley - Nature Reviews Genetics, 2003 - nature.com
Trypanosomatid protozoans cause important diseases of humans and their domestic
livestock. Various molecular genetic tools are now allowing rapid progress in understanding …