[HTML][HTML] Platelets and their role in hemostasis and thrombosis—From physiology to pathophysiology and therapeutic implications

A Scridon - International Journal of Molecular Sciences, 2022 - mdpi.com
Hemostasis is a physiological process critical for survival. Meanwhile, thrombosis is
amongst the leading causes of death worldwide, making antithrombotic therapy one of the …

Platelets in thrombosis and hemostasis: old topic with new mechanisms

Y Wang, M Andrews, Y Yang, S Lang… - … Current Drug Targets …, 2012 - ingentaconnect.com
Platelets are small anucleate cells generated from megakaryocytes in the bone marrow.
After being released into the circulation, platelets play key roles in the surveillance of …

Platelets in inflammation and thrombosis

DD Wagner, PC Burger - Arteriosclerosis, thrombosis, and …, 2003 - Am Heart Assoc
For many years it has been known that platelets play an important role in thrombosis and
hemostasis. In recent times, however, it has become evident that platelets also have relevant …

Historical overview of the role of platelets in hemostasis and thrombosis

G De Gaetano - haematologica, 2001 - haematologica.org
Platelets were discovered by G. Bizzozero in 1882 and rediscovered in the 1960s after many
decades of oblivion. Interestingly enough, their role was initially more clearly associated with …

[HTML][HTML] An insight into recent advances on platelet function in health and disease

PK Chaudhary, S Kim, S Kim - International journal of molecular sciences, 2022 - mdpi.com
Platelets play a variety of roles in vascular biology and are best recognized as primary
hemostasis and thrombosis mediators. Platelets have a large number of receptors and …

[HTML][HTML] Physiology, platelet

JH Fountain, SL Lappin - 2017 - europepmc.org
Platelets are small blood cells with several physiological purposes; the best studied is
thrombosis activation. Through their clotting activity and activation of the coagulation …

[图书][B] Platelets in thrombotic and non-thrombotic disorders: pathophysiology, pharmacology and therapeutics: an update

P Gresele, NS Kleiman, JA Lopez, CP Page - 2017 - books.google.com
This book reviews current science and applications in fields including thrombosis and
hemostasis, signal transduction, and non-thrombotic conditions such as inflammation …

[HTML][HTML] Mechanism action of platelets and crucial blood coagulation pathways in hemostasis

MH Periayah, AS Halim, AZM Saad - International journal of …, 2017 - ncbi.nlm.nih.gov
Blood is considered to be precious because it is the basic necessity for health; our body
needs a steady provision of oxygen, supplied via blood, to reach billions of tissues and cells …

[PDF][PDF] The biology of the platelet with special reference to inflammation, wound healing and immunity

AT Nurden - Front Biosci (Landmark Ed), 2018 - researchgate.net
While platelets have long been known to be essential for maintaining hemostasis in the
vasculature, their role in tissue repair, inflammation and innate and adaptive immunity is a …

Interplay between platelets and coagulation

Y Sang, M Roest, B de Laat, PG de Groot, D Huskens - Blood reviews, 2021 - Elsevier
Haemostasis stops bleeding at the site of vascular injury and maintains the integrity of blood
vessels through clot formation. This regulated physiological process consists of complex …