Aged individuals are at risk to experience slow and incomplete muscle recovery following
periods of disuse atrophy. While several therapies have been employed to mitigate muscle …

Aging coincides with the progressive loss of muscle mass and strength, increased adiposity,
and diminished physical function. Accordingly, interventions aimed at improving muscle …

Age-related decline in integrity and function of differentiated adult tissues is widely attributed
to reduction in number or regenerative potential of resident stem cells. The satellite cell …

The most studied sources of mesenchymal stem/stromal cells (MSCs) are bone marrow and
adipose tissue. However skeletal muscle represents an interesting source of diverse …

Human pluripotent stem cell (hPSC)-derived myogenic progenitor cell (MPC) transplantation
is a promising therapeutic approach for a variety of degenerative muscle disorders. Here …

Age‐related declines in skeletal muscle regeneration have been attributed to muscle stem
cell (MuSC) dysfunction. Aged MuSCs display a fibrogenic conversion, leading to fibrosis …

Background: Rotator cuff tears (RCTs) induce chronic muscle weakness and shoulder pain.
Treatment of RCT using surgery or drugs causes lipid infiltration and fibrosis, which hampers …

Satellite cells are unipotent stem cells involved in muscle regeneration. However, the
skeletal muscle microenvironment exerts a dominant influence over stem cell function. The …

Highlights•Muscle stem cell function loss contributes to reduced strength in old age.•Single
cell technologies reveal exciting details of muscle biology during aging.•Muscle Cellular …

The use of adult skeletal muscle stem cells (MuSCs) for cell therapy has been attempted for
decades, but still encounters considerable difficulties. MuSCs derived from human induced …