Advanced drug delivery systems often employ nanomaterials as carriers to deliver drugs to
desirable disease sites for enhanced efficacy. However, most systems have low drug …

The efficient delivery of antitumor agents to tumor sites faces numerous obstacles, such as
poor cellular uptake and slow intracellular drug release. In this regard, smart nanoparticles …

Programmable drug delivery systems hold great promise to enhance cancer treatment.
Herein, a programmable drug delivery system using a chondroitin sulfate (CS)-based …

Constructing highly efficient and multifunctional nanoparticles to overcome the multiple
challenges of targeted drug delivery is a new strategy urgently needed in tumor therapy …

Tumor-responsive nanocarriers are highly valuable and demanded for smart anticancer
drug delivery, where a quick release of chemotherapeutic drugs in tumors is preferred …

Efficient delivery of therapeutics into tumor cells to increase the intracellular drug
concentration is a major challenge for cancer therapy due to drug resistance and inefficient …

Abstract pH-Responsive nanoparticles (NPs) have emerged as an effective antitumor drug
delivery system, promoting the drugs accumulation in the tumor and selectively releasing …

To face the growing demand of polymeric nanoparticles with biocompatibility and a drug
release profile, in this work, a novel carboxymethylcellulose-based pH and redox dual …

We report the synthesis of novel acid-responsive therapeutic nanoparticles (NPs) with sub-
100 nm size consisting of polymer− cisplatin conjugates. The uniqueness of these drug …

Multidrug resistance (MDR) remains a serious impediment to successful tumor
chemotherapy. Despite considerable efforts to address MDR, limited approaches have been …