Atividade antimicrobiana e mecanismo de ação de peptídeos sintéticos bioinspirados em JcTI-I, um inibidor de tripsina de Jatropha curcas

LAL Souza - 2023 - repositorio.ufc.br
In recent years, the increase in microbial resistance has caused concern and represents a
serious public health problem, causing thousands of deaths worldwide. Thus, the discovery …

JcTI-PepI, a synthetic peptide bioinspired in the trypsin inhibitor from Jatropha curcas, presents potent inhibitory activity against C. krusei, a neglected pathogen

LAL Souza, LP Dias, NMS Araújo, RF Carneiro… - Biochimie, 2022 - Elsevier
Antimicrobial resistance has been increasing globally, posing a global public health risk. It
has prompted the scientific community to look for alternatives to traditional drugs …

ClTI-Pep, um peptídeo sintético antimicrobiano bioinspirado no inibidor de tripsina da Cassia leiandra Benth., exerce efeito tóxico in vitro contra MRSA e Candida …

NMS Araújo - 2023 - repositorio.ufc.br
Antimicrobial resistance, despite being neglected, has been a major global crisis in public
health in recent decades. With the advent of the COVID-19 pandemic, the current concern …

JcTI-I: a novel trypsin inhibitor from Jatropha curcas seed cake with potential for bacterial infection treatment

HPS Costa, JTA Oliveira, DOB Sousa… - Frontiers in …, 2014 - frontiersin.org
Jatropha curcas seed cake is a low-value by-product resulting from biodiesel production.
The seed cake is highly toxic, but it has great potential for biotechnology applications as it is …

Purificação e caracterização de um inibidor de tripsina com atividade antimicrobiana da torta de pinhão-manso (Jatropha curcas L.)

HPS Costa - 2012 - repositorio.ufc.br
RESUMO O resíduo (torta) obtido após a extração de óleo das sementes de pinhão-manso
(Jatropha curcas) para a produção de biodiesel é tóxico. Apesar dos entraves relacionados …

Desenvolvimento de um novo peptídeo com atividade antimicrobiana (bactérias e leveduras) e antiproliferativa em células neoplásicas: análises in silico, in vitro e in …

LHDEO ALMEIDA - 2023 - repositorio.ufms.br
Antimicrobial resistance (AMR) acquired by microorganisms, whether naturally or due to the
indiscriminate use of antimicrobials, and multidrug resistance (MRD) acquired by …

P002 Antifungal activity of antimicrobial synthetic peptides against Candida species of public health importance

R Torres, A Barreto-Santamaría… - Medical …, 2022 - academic.oup.com
Abstract Poster session 1, September 21, 2022, 12: 30 PM-1: 30 PM Background
Candidiasis is one of the most frequent opportunistic infections in immunosuppressed …

[HTML][HTML] In Silico predicted antifungal peptides: in Vitro and in vivo anti-candida activity

T Ciociola, W Magliani, T De Simone, TA Pertinhez… - Journal of Fungi, 2021 - mdpi.com
It has been previously demonstrated that synthetic antibody-derived peptides could exert a
significant activity in vitro, ex vivo, and/or in vivo against microorganisms and viruses, as well …

DESENHO DE UM NOVO PEPTÍDEO ANTIMICROBIANO ULTRACURTO GUIADO POR FERRAMENTAS COMPUTACIONAIS

MCDEM CAVALHEIRO - 2022 - repositorio.ufms.br
Antimicrobial peptides have different sites of action than conventional antibiotics. Recent
research has been looking for peptides capable of controlling multidrug-resistant bacteria …

[PDF][PDF] Avaliação do potencial antifúngico do peptídeo 8WHst-5Duo contra Candida albicans

MMF Portella - 2023 - repositorio.unesp.br
O combate à candidíase tem se tornado cada vez mais difícil devido à resistência que sua
principal causadora, a espécie fúngica Candida albicans, tem adquirido aos medicamentos …