Aim Visceral leishmaniasis (VL) caused by parasites belonging to genus Leishmania (L.) is
classified as a category I disease by the TDR/WHO. The understanding of the pathogenesis …

Several animal models have been established to study visceral leishmaniosis (VL), a
worldwide vector-borne disease affecting humans and domestic animals that constitutes a …

Visceral leishmaniases (VL) or kala-azar is the most dreaded and devastating amongst the
various forms of leishmaniases. The disease, though localized in certain areas only, has …

Background Cutaneous leishmaniasis is a tropical disease affecting over one million
patients annually and Leishmania (L.) mexicana is one of the major etiological agents in the …

Publisher Summary Visceral leishmaniasis (VL) is caused by haemoflagellate protozoan
parasites belonging to the genus Leishmania, particularly the species Leishmania donovani …

The clinical manifestation of leishmaniases depends on parasite species, host genetic
background, and immune response. Manifestations of human leishmaniases are highly …

Improved animal models are urgently required for drug and vaccine development against
visceral leishmaniasis. Here we report refinements to the hamster model of infection that …

In public health terms, leishmaniases are diseases of humans and dogs, whereas, in
epidemiological terms, Leishmania spp. are considered to represent infections of a wide …

For experimental infections with viscerotropic strains of Leishmania, a suitable animal model
is not yet defined. In the present work, we have reappraised the use of golden hamster …

This unit focuses on the murine model of cutaneous leishmaniasis and models of visceral
leishmaniasis in mice and hamsters. Each basic protocol describes the methods used to …