[HTML][HTML] Biomolecular interactions of ultrasmall metallic nanoparticles and nanoclusters

AA Sousa, P Schuck, SA Hassan - Nanoscale Advances, 2021 - pubs.rsc.org
The use of nanoparticles (NPs) in biomedicine has made a gradual transition from proof-of-
concept to clinical applications, with several NP types meeting regulatory approval or …

[HTML][HTML] Research Update: Interfacing ultrasmall metal nanoclusters with biological systems

L Shang, GU Nienhaus - APL materials, 2017 - pubs.aip.org
Metal nanoclusters (NCs), a new type of nanomaterial with unique physicochemical
properties, show great potential in many biomedical applications. Understanding their …

[HTML][HTML] Open questions on proteins interacting with nanoclusters

R Antoine, D Maysinger, L Sancey… - Communications …, 2022 - nature.com
Interfacing ultrasmall metal nanoclusters (NCs) with proteins can present a dual opportunity:
proteins can be used for protecting NCs, and the surface ligands of NCs may interact with …

Bio-NCs–the marriage of ultrasmall metal nanoclusters with biomolecules

N Goswami, K Zheng, J Xie - Nanoscale, 2014 - pubs.rsc.org
Ultrasmall metal nanoclusters (NCs) have attracted increasing attention due to their
fascinating physicochemical properties. Today, functional metal NCs are finding growing …

A model beyond protein corona: thermodynamics and binding stoichiometries of the interactions between ultrasmall gold nanoclusters and proteins

MM Yin, WQ Chen, YQ Lu, JY Han, Y Liu, FL Jiang - Nanoscale, 2020 - pubs.rsc.org
Nanoparticles (NPs) will inevitably interact with proteins and form protein coronas once they
are exposed to biological fluids. This conventional model for nano–bio interactions has been …

Time Evolution of Ultrasmall Gold Nanoparticle–Protein Interactions

AF Lima, VS Guido, N Mina, RJS Torquato, AA Sousa - Langmuir, 2023 - ACS Publications
To date, much effort has been devoted toward the study of protein corona formation onto
large gold nanoparticles (GNPs). However, the protein corona concept breaks down for …

Mechanistic insights into ultrasmall gold nanoparticle–protein interactions through measurement of binding kinetics

RS Ferreira, AL Lira, RJS Torquato… - The Journal of …, 2019 - ACS Publications
Gold nanoparticles (NPs) in the ultrasmall size regime provide a new paradigm in the way
that nanomaterials can be used to regulate protein structure and function. However, the …

Binding kinetics of ultrasmall gold nanoparticles with proteins

AL Lira, RS Ferreira, RJS Torquato, H Zhao, MLV Oliva… - Nanoscale, 2018 - pubs.rsc.org
Synthetic ultrasmall nanoparticles (NPs) can be designed to interact with biologically active
proteins in a controlled manner. However, the rational design of NPs requires a clear …

[HTML][HTML] Functionalization of metal nanoclusters for biomedical applications

XR Song, N Goswami, HH Yang, J Xie - Analyst, 2016 - pubs.rsc.org
Metal nanoclusters (NCs) are emerging as a new class of functional nanomaterials in the
area of biological sensing, labelling, imaging and therapy due to their unique physical and …

Regimes of biomolecular ultrasmall nanoparticle interactions

L Boselli, E Polo, V Castagnola… - Angewandte …, 2017 - Wiley Online Library
Ultrasmall nanoparticles (USNPs), usually defined as NPs with core in the size range 1–3
nm, are a class of nanomaterials which show unique physicochemical properties, often …