Current treatment of Parkinson's disease (PD) ameliorates symptoms but fails to block
disease progression. This study was conducted to explore the protective effects of SVHRSP …

Background Inflammation plays an important role in the pathogenesis of Parkinson's
disease (PD) through over-activation of microglia, which consequently causes the excessive …

Abstract Ethnopharmacological relevance In traditional Chinese medicine, scorpion is used
to treat diseases with symptoms such as trembling, convulsion and dementia. Our laboratory …

Background and Purpose Microglia‐related inflammation is associated with the pathology of
Parkinson's disease. Functional voltage‐gated sodium channels (VGSCs) are involved in …

Neuroprotective effect of scorpion venom on Parkinson's disease (PD) has already been
reported. The present study was aimed to investigate whether scorpion venom heat resistant …

The neuromodulator hydrogen sulfide (H2S) was shown to exert neuroprotection in different
models of Parkinson's disease (PD) via its anti-inflammatory and anti-apoptotic properties. In …

Oxidative stress damage plays a pivotal role in Parkinson's disease (PD) pathogenesis.
Previously, we developed a blood brain barrier-penetrating peptide-based “Trojan Horse” …

Unregulated microglial activation has been implicated as a pivotal factor contributing to
Parkinson's disease. Using mesencephalic neuron‐glia cultures, we address the novel …

Microglia-associated inflammatory processes have been strongly implicated in the
development and progression of Parkinson's disease (PD). Specifically, microglia are …

Inflammation has been increasingly recognized to contribute to the pathogenesis of
Parkinson's disease. Several compounds are neuroprotective at femtomolar concentrations …