Bronchial Epithelial Cells on the Front Line to Fight Lung Infection-Causing Aspergillus fumigatus

J Bigot, L Guillot, J Guitard, M Ruffin, H Corvol… - Frontiers in …, 2020 - frontiersin.org
Aspergillus fumigatus is an environmental filamentous fungus that can be pathogenic for
humans, wherein it is responsible for a large variety of clinical forms ranging from allergic …

Interaction of the pathogenic mold Aspergillus fumigatus with lung epithelial cells

N Osherov - Frontiers in microbiology, 2012 - frontiersin.org
Aspergillus fumigatus is an opportunistic environmental mold that can cause severe allergic
responses in atopic individuals and poses a life-threatening risk for severely …

The innate immune response to Aspergillus fumigatus at the alveolar surface

A Margalit, K Kavanagh - FEMS microbiology reviews, 2015 - academic.oup.com
Aspergillus fumigatus is an ubiquitous, saprophytic mould that forms and releases airborne
conidia which are inhaled by humans on a daily basis. When the immune system is …

[HTML][HTML] The innate immune response to Aspergillus fumigatus

V Balloy, M Chignard - Microbes and infection, 2009 - Elsevier
Despite the development of new treatments, the mortality due to invasive pulmonary
aspergillosis remains above 50%, reaching 95% in certain situations. The battle against …

Host defense mechanisms against Aspergillus fumigatus lung colonization and invasion

JJ Mackel, C Steele - Current opinion in microbiology, 2019 - Elsevier
The human lung is continually exposed to airborne conidia of the fungus Aspergillus
fumigatus (AF) and related species. The innate immune system efficiently eliminates inhaled …

Interactions of Aspergillus fumigatus Conidia with Airway Epithelial Cells: A Critical Review

CA Croft, L Culibrk, MM Moore, SJ Tebbutt - Frontiers in microbiology, 2016 - frontiersin.org
Aspergillus fumigatus is an environmental filamentous fungus that also acts as an
opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a …

The Immune Interplay between the Host and the Pathogen in Aspergillus fumigatus Lung Infection

H Sales-Campos, L Tonani… - BioMed research …, 2013 - Wiley Online Library
The interplay between Aspergillus fumigatus and the host immune response in lung
infection has been subject of studies over the last years due to its importance in …

Innate lung defense during invasive aspergillosis: new mechanisms

JM Garth, C Steele - Journal of innate immunity, 2017 - karger.com
Invasive aspergillosis (IA) is one of the most difficult to treat and, consequently, one of the
most lethal fungal infections known to man. Continued use of immunosuppressive agents …

Interference of Aspergillus fumigatus with the immune response

T Heinekamp, H Schmidt, K Lapp, V Pähtz… - Seminars in …, 2015 - Springer
Aspergillus fumigatus is a saprotrophic filamentous fungus and also the most prevalent
airborne fungal pathogen of humans. Depending on the host's immune status, the variety of …

Expression profile analysis reveals that Aspergillus fumigatus but not Aspergillus niger makes type II epithelial lung cells less immunological alert

N Escobar, ID Valdes, EM Keizer, SR Ordonez… - BMC genomics, 2018 - Springer
Background Aspergillus fumigatus is the main causative agent of aspergillosis. Infections
rarely occur in immunocompetent individuals, indicating efficient clearance of conidia by …