Introduction: Anorexia nervosa (AN) is a mental disorder with the highest death rate. The
characteristic feature of AN is endocrine dysregulations, including changes in adipose …

Objective: To review the literature regarding the role of leptin in psychiatric disorders.
Methods: A PubMed search was undertaken using the following keywords: leptin, psychosis …

Leptin is a hormone with pleiotropic functions affecting several tissues. Because leptin has a
crucial role in the adaptation of an organism to semi-starvation, anorexia nervosa (AN) …

Background Leptin, a hormone secreted by adipose tissue, appears to play a major role in
the homeostasis of body weight and psychobiological processes associated with anorexia …

OBJECTIVES: Anorexia nervosa (AN) often presents with comorbid depressive symptoms
and is characterized by low levels of neuroimmunomodulatory hormone–leptin. Treatment …

Anorexia nervosa (AN) has the highest mortality rate between psychiatric disorders, and
evidence for managing it is still very limited. So far, pharmacological treatment has focused …

Serum levels of leptin are decreased in underweight AN patients and increase with weight
restoration. To assess the relationship of decreased leptin levels with other hormonal …

A decreased production of leptin has been reported in women with anorexia nervosa (AN)
and has been attributed merely to the patients' reduced body fat mass. The extent to which …

Leptin is an adipocyte-derived hormone, which is involved predominantly in the long-term
regulation of body weight and energy balance by acting as a hunger suppressant signal to …

Leptin, a protein secreted by adipocytes, has a regulatory function in several organism
systems such as the immune, respiratory, and reproductive systems and in the energy …