The role of miRNAs in drug resistance and prognosis of breast cancer formalin-fixed paraffin-embedded tissues

X Chen, P Lu, D Wang, S Yang, Y Wu, HY Shen… - Gene, 2016 - Elsevier
Purpose Chemoresistance mediated by miRNAs in breast cancer have been already
validated by previous studies in vitro, while little is known concerning the expression of them …

Critical analysis of the potential for microRNA biomarkers in breast cancer management

CR Graveel, HM Calderone, JJ Westerhuis… - Breast cancer: targets …, 2015 - Taylor & Francis
Breast cancer is a complex and heterogeneous disease. Signaling by estrogen receptor
(ER), progesterone receptor (PR), and/or human EGF-like receptor 2 (HER2) is a main driver …

MicroRNAs and noncoding RNAs as gene regulators and potential therapeutic agents

T Juneja, S Shah - Breast cancer: from bench to personalized medicine, 2022 - Springer
Breast cancer is highest prevailing cancer that incredibly affects women also globally it is the
prominent reason of cancer-related mortality. The untranslated transcripts, called noncoding …

Cell-free miRNAs as non-invasive biomarkers in breast cancer: Significance in early diagnosis and metastasis prediction

D Kashyap, H Kaur - Life sciences, 2020 - Elsevier
Breast cancer is one of the genetic diseases causing a high mortality among women around
the world. Despite the availability of advanced diagnostic tools and treatment strategies, the …

MicroRNAs as biomarkers for early breast cancer diagnosis, prognosis and therapy prediction

FJ Nassar, R Nasr, R Talhouk - Pharmacology & therapeutics, 2017 - Elsevier
Breast cancer is a major health problem that affects one in eight women worldwide. As such,
detecting breast cancer at an early stage anticipates better disease outcome and prolonged …

[HTML][HTML] MicroRNAs in pathogenesis of breast cancer: Implications in diagnosis and treatment

NR Shah, H Chen - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding RNAs generated by a two-step complex process
and are post transcriptional negative regulators of their target mRNAs. Dysregulation of …

microRNAs in breast cancer: regulatory roles governing the hallmarks of cancer

JN Goh, SY Loo, A Datta, KS Siveen… - Biological …, 2016 - Wiley Online Library
ABSTRACT A large number of etiological factors and the complexity of breast cancers
present challenges for prevention and treatment. Recently, the emergence of microRNAs …

MicroRNAs as the critical regulators of Doxorubicin resistance in breast tumor cells

AS Zangouei, M Alimardani, M Moghbeli - Cancer Cell International, 2021 - Springer
Background Chemotherapy is one of the most common treatment options for breast cancer
(BC) patients. However, about half of the BC patients are chemotherapeutic resistant …

Role of miR-155 in drug resistance of breast cancer

D Yu, M Lv, W Chen, S Zhong, X Zhang, L Chen, T Ma… - Tumor Biology, 2015 - Springer
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expressions at
posttranscriptional level. Growing evidence points to their significant role in the acquisition of …

miRNA in a multiomic context for diagnosis, treatment monitoring and personalized management of metastatic breast cancer

P Zubor, P Kubatka, Z Dankova, A Gondova… - Future …, 2018 - Taylor & Francis
Metastatic breast cancer is characterized by aggressive spreading to distant organs. Despite
huge multilevel research, there are still several important challenges that have to be clarified …