The role of macrophages in the pathogenesis of SARS-CoV-2-associated acute respiratory distress syndrome
A Kosyreva, D Dzhalilova, A Lokhonina… - Frontiers in …, 2021 - frontiersin.org
Macrophages are cells that mediate both innate and adaptive immunity reactions, playing a
major role in both physiological and pathological processes. Systemic SARS-CoV-2 …
major role in both physiological and pathological processes. Systemic SARS-CoV-2 …
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than
200,000 deaths worldwide. Several studies have now established that the …
200,000 deaths worldwide. Several studies have now established that the …
Monocytes and macrophages, targets of severe acute respiratory syndrome coronavirus 2: the clue for coronavirus disease 2019 immunoparalysis
Abstract Background Coronavirus disease 2019 (COVID-19) clinical expression is
pleiomorphic, severity is related to age and comorbidities such as diabetes and …
pleiomorphic, severity is related to age and comorbidities such as diabetes and …
Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …
A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
Abstract The COVID-19-, SARS-and MERS-related coronaviruses share many genomic and
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …
Macrophages and dendritic cells are not the major source of pro-inflammatory cytokines upon SARS-CoV-2 infection
MA Niles, P Gogesch, S Kronhart… - Frontiers in …, 2021 - frontiersin.org
The exact role of innate immune cells upon infection with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and their contribution to the formation of the corona virus …
coronavirus 2 (SARS-CoV-2) and their contribution to the formation of the corona virus …
Monocytes and Macrophages in COVID-19
COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing
pandemic with massive global health and socioeconomic consequences. The disease is …
pandemic with massive global health and socioeconomic consequences. The disease is …
Macrophage activation syndrome and COVID-19
R Otsuka, K Seino - Inflammation and regeneration, 2020 - Springer
An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating
pandemic. As we have not developed curative medicine and effective vaccine, the end of …
pandemic. As we have not developed curative medicine and effective vaccine, the end of …
Targeting macrophages as a therapeutic option in coronavirus disease 2019
M Gracia-Hernandez, EM Sotomayor… - Frontiers in …, 2020 - frontiersin.org
Immune cells of the monocyte/macrophage lineage are characterized by their diversity,
plasticity, and variety of functions. Among them, macrophages play a central role in antiviral …
plasticity, and variety of functions. Among them, macrophages play a central role in antiviral …
Role of monocytes/macrophages in Covid-19 pathogenesis: implications for therapy
J Gómez-Rial, I Rivero-Calle, A Salas… - Infection and Drug …, 2020 - Taylor & Francis
cov-Abstract Emerging studies from SARS-CoV-2-infected patients indicate a preponderant
role of monocytes/macrophages in the pathogenesis of this viral infection, in a similar way to …
role of monocytes/macrophages in the pathogenesis of this viral infection, in a similar way to …
In the eye of the COVID-19 cytokine storm
N Vaninov - Nature Reviews Immunology, 2020 - nature.com
Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …