Nucleic acid amplification based detection plays an important role in food safety,
environmental monitoring and clinical diagnosis. However, traditional nucleic acid detection …

The use of magnetic nanoparticles (MNPs) in sample preparation has gained much
attention. Easy-to-handle property of MNPs has provided a great promising solution for lab …

This work presents sensitive detection of bacterial genomic DNA using a magnetic
nanoparticle-based substrate-free method. For the first time, such a method is employed for …

Nucleic acid is the main material for storing, copying, and transmitting genetic information.
Gene sequencing is of great significance in DNA damage research, gene therapy, mutation …

Molecular diagnosis is the field that aims to develop nucleic-acid-based analytical methods
for biological markers and gene expression assessments by combining laboratory medicine …

Nucleic acid detection (NAD) based on real-time polymerase chain reaction (real-time PCR)
is gold standard for infectious disease detection. Magnetic nanoparticles (MNPs) are widely …

Nucleic acid extraction represents the “first step” in molecular diagnostic experiments. The
quality of this extraction serves as a fundamental prerequisite for ensuring the accuracy of …

Magnetic nanoparticles have attracted significant attention in various disciplines, including
engineering and medicine. Microfluidic chips and lab-on-a-chip devices, with precise control …

Colloidal magnetic particles (MPs) have been developed in association with molecular
diagnosis for several decades. MPs have the great advantage of easy manipulation using a …

Magnetic particles are useful for simple and efficient nucleic acid extraction. To achieve fully
automated nucleic acid extraction and purification using magnetic particles, a new method …