Antibiotic resistance genes predate the therapeutic uses of antibiotics. However, the current
antimicrobial resistance crisis stems from our extensive use of antibiotics and the generation …

Antibiotic resistance is a global health challenge, involving the transfer of bacteria and
genes between humans, animals and the environment. Although multiple barriers restrict the …

The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …

Antibiotic natural products are ancient and so is resistance. Consequently, environmental
bacteria harbor numerous and varied antibiotic resistance elements. Nevertheless, despite …

Antibiotics are among the most valuable compounds used for fighting human diseases.
Unfortunately, pathogenic bacteria have evolved towards resistance. One important and …

The evolution of bacterial pathogens towards antibiotic resistance is not just a relevant
problem for human health, but a fascinating example of evolution that can be studied in real …

Several interconnected human, animal and environmental habitats can contribute to the
emergence, evolution and spread of antibiotic resistance, and the health of these contiguous …

Antibiotics promote the spread of resistance in the clinic, but various mechanisms may exist
in natural environments that tilt the balance toward antibiotic sensitivity. Studying such …

Antibiotic resistance currently causes hundreds of thousands of deaths worldwide; it is a
major and growing public health threat globally. The origins of many resistance genes in …

Antibiotic resistance is one of the major problems facing medical practice in the 21st century.
Historical approaches to managing antibiotic resistance have often focused on individual …