Background: Antibiotic-resistant pathogens became a real global threat to human and
animal health. This needs to concentrate the efforts to minimize and control these …

Background: Antibiotic-resistant pathogens became a real global threat to human and
animal health. This needs to concentrate the efforts to minimize and control these …

The research and development of specific, potent efflux pump inhibitors (EPIs) appears to be
an important goal for the improved control of infectious diseases. In recent years, different …

Background: Inhibition of efflux pumps, one of the resistance mechanisms can be achieved
by using suitable efflux pump inhibitors. However, the inhibitors are mostly toxic. Therefore …

Objective: Traditional antibiotics are increasingly suffering from the emergence of efflux
related multidrug resistance (MDR) amongst pathogenic bacteria that led to novel …

Rapid increase of multidrug resistance in bacteria has made the discovery of new
antimicrobials necessary. From the time of discovery of bacterial efflux pumps in 1980, many …

Microorganisms affect every aspect of our lives. Especially pathogenic and resistant
microorganisms are microorganisms that prevent us from living a healthy life. As a result of …

The impact of Staphylococcus aureus infections on human health has led to intensive
investigation of this organism over recent years. Antibiotic resistance in Staphylococcus …

Staphylococcus aureus is one of the most common human pathogens that causes wide
range of nosocomial and community acquired infections as wound and burn infections, food …

Expression of bacterial efflux pump is one of the major causes for developing antibiotic
resistance in a variety of pathogens. Efflux pump inhibitors (EPIs) are potential molecules …