The Use of ctDNA in the Diagnosis and Monitoring of Hepatocellular Carcinoma—Literature Review

A Kopystecka, R Patryn, M Leśniewska… - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and is one of the
leading causes of cancer-related deaths worldwide. Despite advances in medicine, it is still …

Current status of ctDNA in precision oncology for hepatocellular carcinoma

Y Li, Y Zheng, L Wu, J Li, J Ji, Q Yu, W Dai… - Journal of Experimental …, 2021 - Springer
The conventional method used to obtain a tumor biopsy for hepatocellular carcinoma (HCC)
is invasive and does not evaluate dynamic cancer progression or assess tumor …

[HTML][HTML] Liquid biopsy using cell-free or circulating tumor DNA in the management of hepatocellular carcinoma

X Lyu, YM Tsui, DWH Ho, IOL Ng - Cellular and Molecular …, 2022 - Elsevier
Liver cancer (hepatocellular carcinoma [HCC]) is a fatal cancer worldwide and often is
detected at an advanced stage when treatment options are very limited. This drives the …

The clinical role of 'liquid biopsy'in hepatocellular carcinoma

JA Howell, R Sharma - Hepatic Oncology, 2016 - Taylor & Francis
Circulating free tumor DNA (ctDNA) is DNA released from necrotic or apoptotic tumor cells
into the bloodstream. Absolute levels of ctDNA, as well as genetic mutations and epigenetic …

[HTML][HTML] Circulating tumor DNA as an emerging liquid biopsy biomarker for early diagnosis and therapeutic monitoring in hepatocellular carcinoma

X Wu, J Li, A Gassa, D Buchner, H Alakus… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
As one of the most common malignant tumors worldwide, hepatocellular carcinoma (HCC) is
known for its poor prognosis due to diagnosis only in advanced stages. Nearly 50% of the …

[HTML][HTML] Role of circulating tumor DNA to help decision-making in hepatocellular carcinoma

J von Felden, AJ Craig, A Villanueva - Oncoscience, 2018 - ncbi.nlm.nih.gov
Liver cancer is the second-most common cause of cancer-related mortality worldwide, and
hepatocellular carcinoma (HCC) accounts for 90% of all cases. According to the current …

[HTML][HTML] ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma

N Biglari, MS Soltani-Zangbar, J Mohammadian… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most prevalent forms of cancer worldwide.
Therefore, it is essential to diagnose and treat HCC patients promptly. As a novel discovery …

Circulating tumor DNA clinical applications in hepatocellular carcinoma: current trends and future perspectives

T Bardol, GP Pageaux, E Assenat… - Clinical …, 2024 - academic.oup.com
Background Globally, liver cancers are the second most lethal malignancy after lung cancer
(0.83 million deaths in 2020). Hepatocellular carcinoma (HCC) is the predominant type of …

Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA

Q Ye, S Ling, S Zheng, X Xu - Molecular cancer, 2019 - Springer
Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of
death worldwide. Due to latent liver disease, late diagnosis, and nonresponse to systemic …

Overview of the role of liquid biopsy in cancer management

T Assi, R Khoury, R Ibrahim, M Baz, T Ibrahim… - Translational …, 2023 - Elsevier
With the emergence of novel targeted therapeutic options in early-stage and advanced-
stage malignancies, researchers have shifted their focus on developing personalized …