The transcription factor high mobility group protein A2 (HMGA2) plays an important role in
the pathogenesis of some cancers including breast cancer. Polyamidoamine dendrimer …

Objective: Cisplatin has limited clinical applications due to drug resistance. PAMAM
dendrimer was chosen as a vehicle to counteract cisplatin-resistance and its mechanism …

One of the most severe health diseases affect the mankind is cancer. The treatment methods
such as magnetic hyperthermia, chemotherapy, photothermal therapy and MRI‐traced …

Taxanes are considered fundamental drugs in the treatment of breast cancer, but despite the
similarities, docetaxel (doc) and paclitaxel (ptx) work differently. For this reason, it is …

Carboplatin (CAR) is a second generation platinum-based compound emerging as one of
the most widely used anticancer drugs to treat a variety of tumors. In an attempt to address …

Lapatinib (L) and fulvestrant (F) are used in targeted anticancer therapies, in particular,
against phenotypically different breast cancer cells. L, a dual inhibitor of EGFR and HER2 …

Polyamidoamine dendrimers, which can deliver drugs and genetic materials to resistant
cells, are attracting increased research attention, but their transportation behavior in …

Polyamidoamine (PAMAM) dendrimers are extensively researched as potential drug
delivery system thanks to their desirable features such as controlled and stable structures …

Canine mammary gland tumor (CMT) is the most common tumor in intact female dog.
Zerumbone (ZER) has promising anticancer properties, but plagued with poor water …

Generation 4 of polyamidoamine dendrimer (G4-PAMAM) has several biological effects due
to its tridimensional globular structure, repetitive branched amides, tertiary amines, and …