Abstract Poly (amidoamine) dendrimers (PAMAM) are well-defined, highly branched,
nanoscale macromolecules with numerous active amine groups on the surface. PAMAM …

Background Poly (amidoamine)(PAMAM) dendrimers are of considerable interest when
used as a carrier for topical drugs for the skin, although little is known about their possible …

Approximately 20% of breast cancer cases are human epidermal growth factor receptor 2
(HER2)-positive. This type of breast cancer is more aggressive and tends to reoccur more …

In the last several decades, researchers have focused on developing suitable drug carriers
to deliver pharmaceutical agents to treat cancer diseases. PAMAM dendrimers have been …

The aim of this work was to synthesize methotrexate (MTX)-polyamidoamine (PAMAM)
dendritic nanoconjugates and to study their effect on cell viability in uterine sarcoma cells …

Irresponsiveness of triple negative breast cancer (TNBC) toward conventional therapies has
drawn attention toward siRNA therapeutics. In gene delivery, dendrimers are gaining …

Dendrimers are one of the most appropriate nanocaries for imaging moieties in imaging
applications. The purpose of this study was the evalution of cytotoxicity and inducing …

Background The notion of cancer therapy is intrinsically subjected to multiple challenges
due to the drug resistance and drug toxicity for normal tissues. Herniarin (7 …

Dendrimers are an excellent candidate that exhibits higher proficiency in biomedical
applications such as drug delivery, inhibition and/or targeting gene delivery. The use of …

The heterogeneity of breast cancer and the development of drug resistance are the relapse
reasons of disease after chemotherapy. To address this issue, a combined therapeutic …