Anionic linear-globular dendrimers: biocompatible hybrid materials with potential uses in nanomedicine

MS Alavidjeh, I Haririan, MR Khorramizadeh… - Journal of Materials …, 2010 - Springer
The use of dendrimers as nano-sized excipients/vectors in biological and pharmaceutical
systems is dependent on the investigation of their toxicological profiles in biological media …

Dendrimer applications for cancer therapies

X Yan, Y Yang, Y Sun - Journal of Physics: Conference Series, 2021 - iopscience.iop.org
Human cancer therapy is a major issue in modern medical science. Lots of emerging
materials are developing rapidly. Dendrimers, as a nanocarrier, are now widely used in the …

Aptamer-grafted, cell membrane-coated dendrimer loaded with doxorubicin as a targeted nanosystem against epithelial cellular adhesion molecule (EpCAM) for triple …

A Sheikh, MAS Abourehab, AS Tulbah… - Journal of Drug Delivery …, 2023 - Elsevier
The major issue associated with chemotherapeutics is the non-specific distribution,
extended range of toxicity, and low intratumoral accumulation. Targeted therapy using …

Generation 4 polyamidoamine dendrimers is a novel candidate of nano-carrier for gene delivery agents in breast cancer treatment

P Wang, XH Zhao, ZY Wang, M Meng, X Li, Q Ning - Cancer letters, 2010 - Elsevier
Polyamidoamine dendrimer (PAMAM-D) is a new gene vector developed in recent years. In
this study, we successfully prepared G4PAMAM and detected its unique structure by NMR …

Acid ground nano‐realgar processed product inhibits breast cancer by inducing mitophagy via the p53/BNIP3/NIX pathway

J Fang, X Zou, L Gong, J Xi, Y Liu… - Journal of Cellular …, 2023 - Wiley Online Library
Breast cancer is a highly prevalent malignancy with the first morbidity and the primary
reason for female cancer‐related deaths worldwide. Acid ground nano‐realgar processed …

Facile formation of PAMAM dendrimer nanoclusters for enhanced gene delivery and cancer gene therapy

SL Mekuria, J Li, C Song, Y Gao, Z Ouyang… - ACS Applied Bio …, 2021 - ACS Publications
Preparation of versatile and safe nanovectors for efficient cancer gene therapy remains to be
challenging in the current nanomedicine. Herein, we report the formation of dendrimer …

Effect of methotrexate conjugated PAMAM dendrimers on the viability of breast cancer cells

SA Torres-Pérez, MP Ramos-Godínez… - AIP Conference …, 2019 - pubs.aip.org
Nanotechnology in recent years, by using nanoparticles (Np) has emerged as an alternative
diagnosis and treatment of breast cancer, being this the most common invasive cancer in …

PAMAM dendrimer as a talented multifunctional biomimetic nanocarrier for cancer diagnosis and therapy

B Surekha, NS Kommana, SK Dubey… - Colloids and Surfaces B …, 2021 - Elsevier
Abstract Poly (amidoamine) dendrimers (PAMAM) are novel polymeric highly branched
architectures with well-defined nano-size, narrow polydispersity index and numerous active …

Cationic poly (amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells

Y Li, S Wang, Z Wang, X Qian, J Fan, X Zeng… - …, 2014 - iopscience.iop.org
Abstract Poly (amidoamine)(PAMAM) dendrimers are proposed as one of the most
promising nanomaterials for biomedical applications because of their unique tree-like …

Intracellular drug release from curcumin-loaded PLGA nanoparticles induces G2/M block in breast cancer cells

P Verderio, P Bonetti, M Colombo, L Pandolfi… - …, 2013 - ACS Publications
PLGA nanoparticles are among the most studied polymer nanoformulations for several
drugs against different kinds of malignant diseases, thanks to their in vivo stability and tumor …