Recent advances in multifunctional dendrimer-based nanoprobes for breast cancer theranostics

P Kesharwani, R Chadar, R Shukla… - Journal of …, 2022 - Taylor & Francis
Breast cancer (BC) undoubtedly is one of the most common type of cancers amongst
women, which causes about 5 million deaths annually. The treatments and diagnostic …

Alteration of the hif-1α/Vegf signaling pathway and disruption of the cell cycle by second generation carbosilan dendrimers

O Barrios, BG Sánchez, T Rodríguez-Prieto… - …, 2022 - ACS Publications
Current therapies against prostate cancer (PCa) disease, such as surgery, radiotherapy, or
in last term chemical castration by androgen deprivation, have led to significant reduction of …

Tumor-induced myeloid cells are reduced by gemcitabine-loaded PAMAM dendrimers decorated with anti-Flt1 antibody

D Yoyen-Ermis, K Ozturk, MA Kursunel… - Molecular …, 2018 - ACS Publications
While reshaping their microenvironment, tumors are also capable of influencing systemic
processes including myeloid cell production. Therefore, the tumor-induced myeloid cells …

Development of functional dendrisomes based on a single molecule of polyesterbenzylether dendrimer and their application in cancer stem cell therapy

LM Mu, L Liu, R Liu, JL Duan, S Ma, XQ Li, YN Cui… - NPG Asia …, 2019 - nature.com
The differentiation therapy of breast cancer stem cells (CSCs) represents a significant
strategy to treat cancer, but inefficient delivery to CSCs hinders the efficacy of differentiation …

Surface modified poly (amido) amine dendrimers as diverse nanomolecules for biomedical applications

VK Yellepeddi, A Kumar… - Expert opinion on drug …, 2009 - Taylor & Francis
The unique properties of poly (amido) amine dendrimers such as nano size, multifunctional
surface, ability to encapsulate and bind the guest molecules, efficient membrane transport …

Polyamidoamine dendrimer decorated graphene oxide as a pH-sensitive nanocarrier for the delivery of hydrophobic anticancer drug quercetin: a remedy for breast …

M Matiyani, A Rana, M Pal, S Dokwal… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives The aim of this study was to investigate the potential of poly (amido
amine)(PAMAM) dendrimer decorated graphene oxide (GO) based nanocarrier for targeted …

In vivo distribution and toxicity of PAMAM dendrimers in the central nervous system depend on their surface chemistry

L Albertazzi, L Gherardini, M Brondi… - Molecular …, 2013 - ACS Publications
Dendrimers have been described as one of the most tunable and therefore potentially
applicable nanoparticles both for diagnostics and therapy. Recently, in order to realize drug …

Curcumin loaded dendrimers specifically reduce viability of glioblastoma cell lines

J Gallien, B Srinageshwar, K Gallo, G Holtgrefe… - Molecules, 2021 - mdpi.com
Glioblastoma (GB) is a deadly and aggressive cancer of the CNS. Even with extensive
resection and chemoradiotherapy, patient survival is still only 15 months. To maintain growth …

The therapeutic efficacy of dendrimer and micelle formulations for breast cancer treatment

S Alven, BA Aderibigbe - Pharmaceutics, 2020 - mdpi.com
Breast cancer is among the most common types of cancer in women and it is the cause of a
high rate of mortality globally. The use of anticancer drugs is the standard treatment …

Influence of dendrimer surface charge on the bioactivity of 2-methoxyestradiol complexed with dendrimers

X Shi, I Lee, X Chen, M Shen, S Xiao, M Zhu, JR Baker… - Soft Matter, 2010 - pubs.rsc.org
We report the complexation of a potential anticancer agent 2-methoxyestradiol (2-ME) with
generation 5 (G5) poly (amidoamine) dendrimers having different surface functional groups …