Edaravone Attenuated Particulate Matter‐Induced Lung Inflammation by Inhibiting ROS‐NF‐κB Signaling Pathway

Y Zeng, G Zhu, M Zhu, J Song, H Cai… - Oxidative Medicine …, 2022 - Wiley Online Library
Background. Particulate matter (PM) exposure is related to mitochondria dysfunction and
airway inflammation. Antioxidant drug edaravone (EDA) is reported to improve the …

[HTML][HTML] Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-κB signaling pathway

J Wang, J Huang, L Wang, C Chen, D Yang… - Journal of thoracic …, 2017 - ncbi.nlm.nih.gov
Background Particulate matter (PM) is a high risk factor for various respiratory diseases and
triggers an inflammatory response in lung tissues. However, the molecular mechanism of the …

[HTML][HTML] GSPE attenuates CSE-induced lung inflammation and emphysema by regulating autophagy via the reactive oxygen species/TFEB signaling pathway

OJ Sul, HW Choi, J Oh, SW Ra - Food and Chemical Toxicology, 2023 - Elsevier
Cigarette smoke can enhance reactive oxygen species (ROS) production in inflammatory
and epithelial cells. Subsequently, ROS enhance autophagy-induced inflammation due to …

[HTML][HTML] Ejiao ameliorates lipopolysaccharide-induced pulmonary inflammation via inhibition of NFκB regulating NLRP3 inflammasome and mitochondrial ROS

Q Yue, W Zhang, S Lin, T Zheng, Y Hou… - Biomedicine & …, 2022 - Elsevier
There is no effective treatment for acute lung injury (ALI) at present. Some studies have
reported the anti-inflammatory effect of Ejiao, but no study has addressed the underlying …

Curcumin ameliorates particulate matter-induced pulmonary injury through bimodal regulation of macrophage inflammation via NF-κB and Nrf2

MK Lee, HD Kim, SH Lee, JH Lee - International Journal of Molecular …, 2023 - mdpi.com
The direct effects of particulate matter (PM) on lung injury and its specific molecular
mechanisms are unclear. However, experimental evidence has shown that oxidative stress …

[HTML][HTML] Induction of neutrophil apoptosis by a Bcl-2 inhibitor reduces particulate matter-induced lung inflammation

X Geng, X Wang, M Luo, M Xing, Y Wu, W Li… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
Background. Environmental particulate matter exposure can cause various respiratory
problems including aggravated asthma, decreased lung function and increased respiratory …

Aerosol-administered adelmidrol attenuates lung inflammation in a murine model of acute lung injury

L Interdonato, R D'amico, M Cordaro, R Siracusa… - Biomolecules, 2022 - mdpi.com
Acute lung injury (ALI) is a common and devastating clinical disorder with a high mortality
rate and no specific therapy. The pathophysiology of ALI is characterized by increased …

Emodin mitigates diesel exhaust particles-induced increase in airway resistance, inflammation and oxidative stress in mice

A Nemmar, S Al-Salam, P Yuvaraju, S Beegam… - Respiratory Physiology …, 2015 - Elsevier
Clinical and experimental studies have reported that short-term exposure to particulate air
pollution is associated with inflammation, oxidative stress and impairment of lung function …

MitoQ alleviates LPS-mediated acute lung injury through regulating Nrf2/Drp1 pathway

L Hou, J Zhang, Y Liu, H Fang, L Liao, Z Wang… - Free Radical Biology …, 2021 - Elsevier
Lipopolysaccharide (LPS) has been known to cause alveolar epithelial cell (AEC) apoptosis
and barrier breakdown that characterize acute lung injury (ALI) and acute respiratory …

Resveratrol relieves particulate matter (mean diameter< 2.5 μm)‐induced oxidative injury of lung cells through attenuation of autophagy deregulation

Y Li, W Qian, D Wang, Y Meng, X Wang… - Journal of Applied …, 2018 - Wiley Online Library
Oxidative stress and inflammation are critically implicated in ambient fine particulate matter
(mean diameter< 2.5 μm; PM2. 5)‐induced lung injury. Autophagy, playing a crucial role in …