Genetic risk of type 2 diabetes modifies the effects of a lifestyle intervention aimed at the prevention of gestational and postpartum diabetes

E Huvinen, J Lahti, MM Klemetti, PH Bergman… - Diabetologia, 2022 - Springer
Aims/hypothesis The aim of this study was to assess the interaction between genetic risk
and lifestyle intervention on the occurrence of gestational diabetes mellitus (GDM) and …

Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations

M Li, ML Rahman, J Wu, M Ding, JE Chavarro… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Objective Women with a history of gestational diabetes mellitus (GDM) have an
exceptionally high risk for type 2 diabetes (T2D). Yet, little is known about genetic …

Lessons learned from lifestyle prevention trials in gestational diabetes mellitus

AM Egan, D Simmons - Diabetic Medicine, 2019 - Wiley Online Library
Gestational diabetes mellitus (GDM) is associated with an increased risk of adverse
outcomes for mother and infant both at birth and later in life. A large body of evidence is now …

Genetic variants of gestational diabetes mellitus: a study of 112 SNPs among 8722 women in two independent populations

M Ding, J Chavarro, S Olsen, Y Lin, SH Ley, W Bao… - Diabetologia, 2018 - Springer
Aims/hypothesis Gestational diabetes mellitus (GDM) is a common complication of
pregnancy that has substantial short-and long-term adverse health implications for women …

Gestational diabetes mellitus can be prevented by lifestyle intervention: the Finnish Gestational Diabetes Prevention Study (RADIEL) a randomized controlled trial

SB Koivusalo, K Rönö, MM Klemetti, RP Roine… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE To assess whether gestational diabetes mellitus (GDM) can be prevented by a
moderate lifestyle intervention in pregnant women who are at high risk for the disease …

Genetic risk of progression to type 2 diabetes and response to intensive lifestyle or metformin in prediabetic women with and without a history of gestational diabetes …

SD Sullivan, KA Jablonski, JC Florez… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE The Diabetes Prevention Program (DPP) trial investigated rates of progression
to diabetes among adults with prediabetes randomized to treatment with placebo, metformin …

Randomised controlled trial of preconception lifestyle intervention on maternal and offspring health in people with increased risk of gestational diabetes: study protocol …

MAJ Sujan, HMS Skarstad, G Rosvold, SL Fougner… - BMJ open, 2023 - bmjopen.bmj.com
Introduction Gestational diabetes mellitus (GDM) is associated with increased risk for type 2
diabetes in the mother and cardiometabolic diseases in the child. The preconception period …

Gestational diabetes: is it preventable?

L Chasan-Taber - American Journal of Lifestyle Medicine, 2012 - journals.sagepub.com
Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy
and is strongly related to subsequent risk of type 2 diabetes. The epidemics of obesity and …

Prevalence of gestational diabetes mellitus in women with a family history of type 2 diabetes in first-and second-degree relatives

C Monod, G Kotzaeridi, T Linder, D Eppel, I Rosicky… - Acta Diabetologica, 2023 - Springer
Aims A family history of type 2 diabetes mellitus (T2DM) markedly increases an individual's
lifetime risk of developing the disease. For gestational diabetes (GDM), this risk factor is less …

Prediction of type 2 diabetes in women with a history of gestational diabetes using a genetic risk score

SH Kwak, SH Choi, K Kim, HS Jung, YM Cho, S Lim… - Diabetologia, 2013 - Springer
Aims/hypothesis Women with a history of gestational diabetes mellitus (GDM) are at
increased risk of future development of type 2 diabetes. Recently, over 65 genetic variants …