Porphyromonas gingivalis: Immune Subversion Activities and Role in Periodontal Dysbiosis

G Hajishengallis, PI Diaz - Current oral health reports, 2020 - Springer
Abstract Purpose of Review This review summarizes mechanisms by which Porphyromonas
gingivalis interacts with community members and the host so that it can persist in the …

Breaking bad: Manipulation of the host response by Porphyromonas gingivalis

G Hajishengallis, RJ Lamont - European journal of immunology, 2014 - Wiley Online Library
Recent metagenomic and mechanistic studies are consistent with a new model of
periodontal pathogenesis. This model proposes that periodontal disease is initiated by a …

Porphyromonas gingivalis-Epithelial Cell Interactions in Periodontitis

E Andrian, D Grenier… - Journal of dental …, 2006 - journals.sagepub.com
Emerging data on the consequences of the interactions between invasive oral bacteria and
host cells have provided new insights into the pathogenesis of periodontal disease. Indeed …

Porphyromonas gingivalis virulence factors involved in subversion of leukocytes and microbial dysbiosis

C Zenobia, G Hajishengallis - Virulence, 2015 - Taylor & Francis
The oral bacterium Porphyromonas gingivalis has special nutrient requirements due to its
asaccharolytic nature subsisting on small peptides cleaved from host proteins. Using …

Dual lifestyle of Porphyromonas gingivalis in biofilm and gingival cells

A Sakanaka, H Takeuchi, M Kuboniwa, A Amano - Microbial pathogenesis, 2016 - Elsevier
Porphyromonas gingivalis is deeply involved in the pathogenesis of marginal periodontitis,
and recent findings have consolidated its role as an important and unique pathogen. This …

The chronicles of Porphyromonas gingivalis: the microbium, the human oral epithelium and their interplay

Ö Yilmaz - Microbiology, 2008 - microbiologyresearch.org
The microbiota of the human oral mucosa consists of a myriad of bacterial species that
normally exist in commensal harmony with the host. Porphyromonas gingivalis, an …

[HTML][HTML] Porphyromonas gingivalis, a Long-Range Pathogen: Systemic Impact and Therapeutic Implications

H Mulhall, O Huck, S Amar - Microorganisms, 2020 - mdpi.com
Periodontitis is an inflammatory disease associated with a dysbiosis of the oral flora
characterized by a chronic sustained inflammation leading to destruction of tooth-supporting …

[HTML][HTML] Porphyromonas gingivalis–host interactions: open war or intelligent guerilla tactics?

G Hajishengallis - Microbes and infection, 2009 - Elsevier
This review summarizes and discusses virulence mechanisms whereby Porphyromonas
gingivalis can persist in the oral cavity. It is proposed that the virulence of P. gingivalis is …

Porphyromonas gingivalis survival skills: Immune evasion

S Zheng, S Yu, X Fan, Y Zhang, Y Sun… - Journal of …, 2021 - Wiley Online Library
Periodontitis is a chronic inflammatory condition that destroys the tooth‐supporting tissues
and eventually leads to tooth loss. As one of the most prevalent oral conditions, periodontitis …

[HTML][HTML] Local and Systemic Effects of Porphyromonas gingivalis Infection

WA Chen, Y Dou, HM Fletcher, DS Boskovic - Microorganisms, 2023 - mdpi.com
Porphyromonas gingivalis, a gram-negative anaerobe, is a leading etiological agent in
periodontitis. This infectious pathogen can induce a dysbiotic, proinflammatory state within …