Prenatal Exposure to Antiseizure Medications and Risk of Epilepsy in Children of Mothers With Epilepsy

JW Dreier, J Christensen, J Igland, M Gissler… - JAMA network …, 2024 - jamanetwork.com
Importance Use of valproate and certain other antiseizure medications (ASMs) in pregnancy
is associated with abnormal fetal brain development with potential long-term implications for …

Association of prenatal exposure to valproate and other antiepileptic drugs with intellectual disability and delayed childhood milestones

CA Daugaard, L Pedersen, Y Sun, JW Dreier… - JAMA network …, 2020 - jamanetwork.com
Importance There is concern about neurodevelopmental outcomes associated with prenatal
exposure to valproate and other antiepileptic drugs (AEDs) among children of mothers with …

Prenatal exposure to antiseizure medication and incidence of childhood-and adolescence-onset psychiatric disorders

JW Dreier, MH Bjørk, S Alvestad, M Gissler… - JAMA …, 2023 - jamanetwork.com
Importance Prenatal antiseizure medication (ASM) exposure has been associated with
adverse early neurodevelopment, but associations with a wider range of psychiatric end …

Association between pregnancy and perinatal outcomes among women with epilepsy

N Razaz, T Tomson, AK Wikström… - JAMA neurology, 2017 - jamanetwork.com
Importance To date, few attempts have been made to examine associations between
exposure to maternal epilepsy with or without antiepileptic drug (AED) therapy and …

Behavioral Outcomes and Neurodevelopmental Disorders Among Children of Women With Epilepsy

MJ Cohen, KJ Meador, DW Loring, AG Matthews… - JAMA …, 2024 - jamanetwork.com
Importance The association of fetal exposure to antiseizure medications (ASMs) with
outcomes in childhood are not well delineated. Objective To examine the association of fetal …

Birth outcomes after prenatal exposure to antiepileptic drugs—A population‐based study

D Kilic, H Pedersen, MIS Kjaersgaard, ET Parner… - …, 2014 - Wiley Online Library
Objective We studied the potential impact of antiepileptic drugs (AED s) on fetal growth and
gestational age at birth. Methods In the Danish Medical Birth Registry, we identified all …

Association of prenatal exposure to antiseizure medication with risk of autism and intellectual disability

MH Bjørk, H Zoega, MK Leinonen, JM Cohen… - JAMA …, 2022 - jamanetwork.com
Importance Women with epilepsy frequently need antiseizure medication (ASM) to prevent
seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to …

The impact of epilepsy and antiseizure medications on pregnancy and neonatal outcomes: A nationwide cohort study

CY Kuo, CF Kuo, LC See, MJ Chiou… - Brain and …, 2023 - Wiley Online Library
Purpose Our objective was to assess the adverse outcomes during pregnancy, as well as for
the fetus and neonates, in women with epilepsy, both with and without the use of antiseizure …

Antiepileptic drugs during pregnancy: what is known and which AEDs seem to be safest?

PB Pennell - Epilepsia, 2008 - Wiley Online Library
Most infants born to women with epilepsy are healthy, but there are increased risks related
to in utero antiepileptic drug (AED) exposure and seizures. Emerging data from pregnancy …

Risk of autism after prenatal topiramate, valproate, or lamotrigine exposure

S Hernández-Díaz, L Straub, BT Bateman… - … England Journal of …, 2024 - Mass Medical Soc
Background Maternal use of valproate during pregnancy has been associated with an
increased risk of neurodevelopmental disorders in children. Although most studies of other …