Cigarette smoking predisposes to the development of multiple diseases involving oxidative
damage. We measured a range of oxidative damage biomarkers to understand which differ …

Background It has been hypothesized that the pathogenesis of diseases induced by
cigarette smoking involves oxidative damage by free radicals. However, definitive evidence …

Background Free radical–induced oxidative damage is thought to be involved in the
pathogenesis of diseases associated with cigarette smoking. We examined the production of …

The authors' interpretation of measured indexes of oxidative stress is considerably less
clear. As with many investigators, the oxidant stress endpoint they focused on was lipid …

Background. Oxidative stress is increasingly important in health research. Therefore, it is
necessary to understand which factors determine basal oxidative stress. This study …

Oxidative stress can contribute to the development of diseases, and may originate from
exposures to toxicants commonly found in air pollution and cigarette smoke such as …

Exposure to environmental tobacco smoke (ETS) has been linked to increased risk of lung
cancer and cardiovascular diseases in nonsmokers. Current research suggests that some of …

Free radicals in cigarette smoke (CS) cause oxidative damage to proteins, DNA, and lipids,
contributing to the pathobiology of atherosclerosis, heart disease, and cancer. In vitro …

Currently lacking are stable and easily measured biomarkers that can reflect oxidative stress
in humans. Fluorescent oxidation products may fulfill all three of these criteria. Fasting …

To assess novel liquid chromatography/mass spectrometric methods for measuring
oxidative damage to nucleic acids and lipids, we compared urinary excretion of 8-hydroxy …