Purpose: To identify the clinical characteristics of SRY-negative male patients and genes
related to male sex reversal, we performed a retrospective study using cases of 46, XX …

Background 46, XX testicular disorder of sex development is a rare genetic syndrome,
characterized by a complete or partial mismatch between genetic sex and phenotypic sex …

The 46, XX testicular disorder of sex development (46, XX testicular DSD) is a rare
phenotype associated with disorder of the sex chromosomes. We describe the clinical …

Background To review the possible mechanisms proposed to explain the etiology of 46, XX
sex reversal by investigating the clinical characteristics and their relationships with …

Conclusion: The 46, XX testicular DSD is a rare form of sex reversal with complex
mechanisms leading to a large spectrum of clinical manifestations ranging from ambiguous …

Abstract 46, XX testicular disorder of sex development (46, XX TDSD) is a relatively rare
condition characterised by the presence of testicular tissue with 46, XX karyotype. The …

Genital tract differentiation and development is a complex process beginning early in
embryonic life. Mutation or translocation of the sex-determining region of the Y chromosome …

Context: Differentiation of testicular tissue in 46, XX individuals is seen either in XX males,
the majority of them with SRY gene, or in individuals, usually SRY (−), with ovotesticular …

We report four patients with SRY-positive 46, XX testicular disorders of sex development (46,
XX-TDSD)(cases 1–4). Case 1 exhibited underdeveloped external genitalia with …

Purpose To investigate the clinical characteristics of different categories of sex-reversed 46,
XX individuals and their relationships with chromosomal karyotype and the SRY gene …