An emerging inference is that vascular cells transfer their biological cargo to recipient cells
by secretion of extracellular vesicles (EVs). This study explored the effects of EVs produced …

Soybean is a rich source of high-quality proteins and an excellent food source of bioactive
peptides. A tripeptide, Leu–Ser–Trp (LSW), was previously identified from soybean as an …

Soy proteins are a rich source of various bioactive peptides. LSW (Leu-Ser-Trp) was
previously identified from thermolysin-digested soy protein hydrolysate as a potent ACE …

Vascular oxidative stress, inflammatory response, and proliferation are crucial mediators of
vascular dysfunction which contribute to the pathology of hypertension. A tripeptide, LRW …

The excessive accumulation of angiotensin II (Ang II) in the vascular microenvironment
promotes vascular dysfunction including vascular endothelial inflammation and remodeling …

The purpose of this study was to study the transport mechanism of LSW (Leu-Ser-Trp), an
angiotensin I-converting enzyme inhibitory tripeptide derived from soybean proteins, using …

Endothelial dysfunction is a common disorder of vascular homeostasis in hypertension
characterized by oxidative stress, malignant migration, inflammatory response, and active …

Excessive proliferation, inflammation, oxidative stress, and migration induced by angiotensin
II (Ang II), occurring in vascular smooth muscle cells (VSMCs) during vascular remodelling …

Abstract Leu-Arg-Trp (LRW), a pea-derived tripeptide, is an isomer of Ile-Arg-Trp (IRW), an
egg-derived tripeptide possessing various health benefits including antihypertensive activity …

The renin angiotensin system (RAS) is a key mediator of blood pressure regulation.
Angiotensin II (Ang II), the active component of RAS, is a potent vasoconstrictor that also …