[HTML][HTML] Tackling COPD: a multicomponent disease driven by inflammation

P Kardos, J Keenan - Medscape General Medicine, 2006 - ncbi.nlm.nih.gov
In recent years, research has revealed more about the factors underlying the pathogenesis
of chronic obstructive pulmonary disease (COPD). In particular, inflammation in the lungs …

[HTML][HTML] Maintenance pharmacotherapy of mild and moderate COPD: what is the evidence?

GT Ferguson - Respiratory medicine, 2011 - Elsevier
Chronic obstructive pulmonary disease (COPD) affects more than 24 million individuals in
the United States, although at least half of the cases are not diagnosed. Proactive diagnosis …

Nonpharmacological interventions in COPD

W Janssens, GM Verleden - European Respiratory Review, 2023 - Eur Respiratory Soc
COPD is recognised as one of the major health challenges for the coming decades. This is
primarily driven by a growing burden of the disease due to persistent exposure to tobacco …

Managing exacerbations of COPD: how much progress have we made?

F Baraldi, M Barrecheguren, A Papi… - COPD in the 21st …, 2024 - books.google.com
The pharmacological treatment of exacerbations of COPD has not significantly changed in
the last decades. The use of short-acting bronchodilators to improve symptoms, systemic …

[HTML][HTML] Are blood eosinophils a prime-time biomarker for COPD management decisions?

I Tsiligianni, AG Kaplan - International Journal of Chronic …, 2018 - Taylor & Francis
COPD is a preventable and treatable disease with patients showing a great disease
heterogeneity with respect to risk of exacerbations, symptomatology and health status. Dual …

Effectiveness versus efficacy trials in COPD: how study design influences outcomes and applicability

A Woodcock, I Boucot, DA Leather… - European …, 2018 - Eur Respiratory Soc
Guidelines for chronic obstructive pulmonary disease (COPD) management are based
largely on results from double-blind randomised controlled trials (RCTs) of efficacy. These …

[HTML][HTML] Inhaled Corticosteroids in Subjects with Chronic Obstructive Pulmonary Disease: An Old, Unfinished History

AS Melani, S Croce, G Fabbri, M Messina, E Bargagli - Biomolecules, 2024 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the major causes of disability and
death. Maintenance use of inhaled bronchodilator (s) is the cornerstone of COPD …

Cost-effectiveness and healthcare budget impact in Italy of inhaled corticosteroids and brochodilators for severe and very severe COPD patients

RD Negro, M Eandi, L Pradelli… - International Journal of …, 2007 - Taylor & Francis
Current practice guidelines for the treatment of COPD recommend the use of combined
inhaled corticosteroids and long-acting bronchodilators in severe and very severe patients …

The clinical management of COPD exacerbations: an update

TN Bonten, MJ Kasteleyn, C Taube… - Expert Review of …, 2016 - Taylor & Francis
Clinical management of chronic obstructive pulmonary disease (COPD) exacerbations is of
high importance because exacerbations reduce quality of life, increase mortality and carry …

Recommendations for the management of COPD

GT Ferguson - Chest, 2000 - Elsevier
Three sets of guidelines for the management of COPD that are widely recognized (from the
European Respiratory Society [ERS], American Thoracic Society [ATS], and British Thoracic …