Introduction Over the last two decades, there has been a significant decrease in the global
cases of malaria. However, since 2015, there has been an increase in the reported cases …

Background Malaria caused by Plasmodium falciparum remains a serious global public
health challenge especially in Africa. Interventions that aim to reduce malaria transmission …

As morbidity and mortality due to malaria continue to decline, the identification of individuals
with a high likelihood of transmitting malaria is needed to further reduce the prevalence of …

Background Naturally acquired immune responses against sexual stages of P. falciparum
can reduce the transmission of malaria from humans to mosquitoes. These antigens are …

Background Natural exposure to gametocytes can result in the development of immunity
against the gametocyte by the host as well as genetic diversity in the gametocyte. This study …

Malaria remains a major public health burden despite approval for implementation of a
partially effective pre-erythrocytic malaria vaccine. There is an urgent need to accelerate …

Background: Malaria elimination remains a priority research agenda with the need for
interventions that reduce and/or block malaria transmission from humans to mosquitoes …

Background Malaria transmission-reducing interventions are key components of malaria
control and elimination [1]. However, little is known about the immune responses directed at …

Background Transmission of malaria from man to mosquito depends on the presence of
gametocytes, the sexual stage of Plasmodium parasites in the infected host. Naturally …

An essential element for continuing transmission of Plasmodium falciparum is the availability
of mature gametocytes in human peripheral circulation for uptake by mosquitoes. Natural …