[HTML][HTML] Decrease in intramuscular lipid droplets and translocation of HSL in response to muscle contraction and epinephrine

C Prats, M Donsmark, K Qvortrup, C Londos… - Journal of lipid …, 2006 - ASBMB
A better understanding of skeletal muscle lipid metabolism is needed to identify the
molecular mechanisms relating intramuscular triglyceride (IMTG) to muscle metabolism and …

Adipocyte differentiation-related protein and OXPAT in rat and human skeletal muscle: involvement in lipid accumulation and type 2 diabetes mellitus

R Minnaard, P Schrauwen, G Schaart… - The Journal of …, 2009 - academic.oup.com
Setting: A disordered lipid metabolism is implicated in the development of skeletal muscle
insulin resistance. Lipid droplet proteins of the PAT [perilipin, adipocyte differentiation …

Muscle lipid metabolism: role of lipid droplets and perilipins

PE Morales, JL Bucarey… - Journal of diabetes …, 2017 - Wiley Online Library
Skeletal muscle is one of the main regulators of carbohydrate and lipid metabolism in our
organism, and therefore, it is highly susceptible to changes in glucose and fatty acid (FA) …

High muscle lipid content in obesity is not due to enhanced activation of key triglyceride esterification enzymes or the suppression of lipolytic proteins

M Li, C Paran, NE Wolins… - American Journal of …, 2011 - journals.physiology.org
The mechanisms underlying alterations in muscle lipid metabolism in obesity are poorly
understood. The primary aim of this study was to compare the abundance and/or activities of …

Mechanisms regulating adipocyte lipolysis

GB Carey - Skeletal muscle metabolism in exercise and diabetes, 1998 - Springer
Mechanisms regulating adipocyte lipolysis are reviewed in three stages. The first stage
examines plasma membrane hormone receptors and G-proteins. The primary regulators of …

Subcellular localization of skeletal muscle lipid droplets and PLIN family proteins OXPAT and ADRP at rest and following contraction in rat soleus muscle

REK MacPherson, EAF Herbst… - American Journal …, 2012 - journals.physiology.org
Skeletal muscle lipid droplet-associated proteins (PLINs) are thought to regulate lipolysis
through protein-protein interactions on the lipid droplet surface. In adipocytes, PLIN2 …

[HTML][HTML] Cellular localization and associations of the major lipolytic proteins in human skeletal muscle at rest and during exercise

RR Mason, RCR Meex, AP Russell, BJ Canny… - PloS one, 2014 - journals.plos.org
Lipolysis involves the sequential breakdown of fatty acids from triacylglycerol and is
increased during energy stress such as exercise. Adipose triglyceride lipase (ATGL) is a key …

Role of PAT proteins in lipid metabolism

C Londos, C Sztalryd, JT Tansey, AR Kimmel - Biochimie, 2005 - Elsevier
One of the central reactions in bodily energy metabolism is lipolysis in adipocytes, the
reaction that governs the release of stored fatty acids from the adipocyte triacylglycerol pool …

Lipid droplet dynamics in skeletal muscle

M Bosma - Experimental Cell Research, 2016 - Elsevier
The skeletal muscle is subjected to high mechanical and energetic demands. Lipid droplets
are an important source of energy substrates for the working muscle. Muscle cells contain a …

Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes

H Miyoshi, JW Perfield, MS Obin… - Journal of cellular …, 2008 - Wiley Online Library
In adipocytes, lipid droplet (LD) size reflects a balance of triglyceride synthesis (lipogenesis)
and hydrolysis (lipolysis). Perilipin A (Peri A) is the most abundant phosphoprotein on the …