Abstract Background 5-Fluorouracil (5-FU) is a good anti-cancer drug, but its prolonged use
results in overexpression of certain enzymes like thymidylate synthase and causes multidrug …

Smart drug delivery systems responding to pH gradient between physiological conditions
and acidic conditions in tumor cells are very crucial for treating cancer. This article describes …

In the current work, we investigated and compared the capability of the monodispersed
chitosan (CS) microspheres, CS coated zinc-based metal-organic framework (CS/Zn-MOF) …

A straightforward nanoprecipitating method was developed to prepare water dispersible
curcumin (CCM)-loaded nanoscale zeolitic imidazolate framework-8 (CCM@ NZIF-8) …

A novel pH-responsive drug carrier for the delivery of specific Docetaxel (DTX)
administration is developed based on a zeolitic imidazolate framework (ZIF-8). Aminating …

Background Baicalin (BAN) has attracted widespread attention due to its low-toxicity and
efficient antitumor activity, but its poor water solubility and low bioavailability severely limit its …

Abstract Zeolitic imidazolate framework-8 (ZIF-8) is a promising material for drug delivery,
but its poor stability limits its wide application. In this work, homogeneous dodecahedral ZIF …

Abstract Zeolitic imidazolate framework-8 (ZIF-8) nanostructures exhibit pH-sensitive drug
release properties, making them highly promising for anticancer drug delivery systems. In …

In this study, we have designed an anticancer drug delivery framework by a one-pot
technique using a zeolitic imidazolate framework (ZIF) as the carrier. The chitosan-coated …

Curcumin as a hydrophobic polyphenol has great potential for tumor therapy, yet its rapid
degradation and hydrophobicity severely impair its therapeutic effect in the clinic. Herein, we …