[HTML][HTML] Genome‑wide analysis reveals the emerging roles of long non‑coding RNAs in cancer
X Ren - Oncology Letters, 2020 - spandidos-publications.com
Cancer is the most intractable human disease that is primarily caused by genetic alterations.
Recently, the general application of microarrays and high‑throughput sequencing …
Recently, the general application of microarrays and high‑throughput sequencing …
Long noncoding RNA and cancer: a new paradigm
A Bhan, M Soleimani, SS Mandal - Cancer research, 2017 - AACR
In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …
Emerging roles of long non‐coding RNA in cancer
A Sanchez Calle, Y Kawamura, Y Yamamoto… - Cancer …, 2018 - Wiley Online Library
Since comprehensive analysis of the mammalian genome revealed that the majority of
genomic products are transcribed in long non‐coding RNA (lnc RNA), increasing attention …
genomic products are transcribed in long non‐coding RNA (lnc RNA), increasing attention …
The regulatory role of long noncoding RNAs in cancer
Y Tang, BB Cheung, B Atmadibrata, GM Marshall… - Cancer letters, 2017 - Elsevier
With the advances in genomic analysis technologies, especially next-generation RNA
sequencing, a large number of new transcripts have been discovered, leading to better …
sequencing, a large number of new transcripts have been discovered, leading to better …
Long noncoding RNAs as new architects in cancer epigenetics, prognostic biomarkers, and potential therapeutic targets
D Meseure, K Drak Alsibai, A Nicolas… - BioMed research …, 2015 - Wiley Online Library
Recent advances in genome‐wide analysis have revealed that 66% of the genome is
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …
[HTML][HTML] Decoding the oncogenic signals from the long non-coding RNAs
R Nadhan, DN Dhanasekaran - Onco, 2021 - mdpi.com
Simple Summary Long non-coding RNAs (lncRNA), which are often referred to as “Genomic
Dark Matter”, are emerging as critical molecules involved in the regulation of multiple …
Dark Matter”, are emerging as critical molecules involved in the regulation of multiple …
[HTML][HTML] Integrative analysis reveals clinical phenotypes and oncogenic potentials of long non-coding RNAs across 15 cancer types
Long non-coding RNAs (lncRNAs) have been shown to contribute to tumorigenesis.
However, surprisingly little is known about the comprehensive clinical and genomic …
However, surprisingly little is known about the comprehensive clinical and genomic …
The role of long noncoding RNAs in cancer: the dark matter matters
Sequencing technology has facilitated a new era of cancer research, especially in cancer
genomics. Using next-generation sequencing, thousands of long noncoding RNAs …
genomics. Using next-generation sequencing, thousands of long noncoding RNAs …
[HTML][HTML] Long non-coding RNAs: the regulatory mechanisms, research strategies, and future directions in cancers
N Gao, Y Li, J Li, Z Gao, Z Yang, Y Li, H Liu… - Frontiers in …, 2020 - frontiersin.org
The development and application of whole genome sequencing technology has greatly
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …
[PDF][PDF] Comprehensive genomic characterization of long non-coding RNAs across human cancers
The discovery of long non-coding RNA (lncRNA) has dramatically altered our understanding
of cancer. Here, we describe a comprehensive analysis of lncRNA alterations at …
of cancer. Here, we describe a comprehensive analysis of lncRNA alterations at …