Extracellular vesicles in cancer therapy

SE Wang - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), including a variety of membrane-enclosed nanosized particles
carrying cell-derived cargo, mediate a major type of intercellular communication in …

Extracellular vesicles and their roles in cancer progression

WH Chang, RA Cerione, MA Antonyak - Cancer cell signaling: Methods …, 2021 - Springer
Extracellular vesicles (EVs) produced by cancer cells function as a unique form of
intercellular communication that can promote cell growth and survival, help shape the tumor …

[HTML][HTML] Extracellular vesicles as drug targets and delivery vehicles for cancer therapy

SV Chitti, C Nedeva, R Manickam, P Fonseka… - Pharmaceutics, 2022 - mdpi.com
Extracellular vesicles (EVs) are particles that are released from cells into the extracellular
space both under pathological and normal conditions. It is now well established that cancer …

Extracellular vesicles in the tumor microenvironment: Therapeutic resistance, clinical biomarkers, and targeting strategies

L Han, J Xu, Q Xu, B Zhang… - Medicinal research …, 2017 - Wiley Online Library
Numerous studies have proved that cell‐nonautonomous regulation of neoplastic cells is a
distinctive and essential characteristic of tumorigenesis. Two way communications between …

Extracellular vesicles as natural therapeutic agents and innate drug delivery systems for cancer treatment: Recent advances, current obstacles, and challenges for …

M Pirisinu, TC Pham, DX Zhang, TN Hong… - Seminars in Cancer …, 2022 - Elsevier
As cancer poses a significant threat to the well-being of humans on a global scale, many
researchers have embarked on the search for effective anticancer therapeutic agents. In …

[HTML][HTML] Basics and applications of tumor-derived extracellular vesicles

YL Tai, PY Chu, BH Lee, KC Chen, CY Yang… - Journal of biomedical …, 2019 - Springer
Extracellular vesicle (EV)-mediated intercellular communication acts as a critical culprit in
cancer development. The selective packaging of oncogenic molecules renders tumor …

Extracellular vesicles as emerging targets in cancer: Recent development from bench to bedside

K Wu, F Xing, SY Wu, K Watabe - … et Biophysica Acta (BBA)-Reviews on …, 2017 - Elsevier
Extracellular vesicles (EVs) have emerged as important players of cancer initiation and
progression through cell-cell communication. They have been recognized as critical …

[HTML][HTML] Extracellular vesicles in the development of cancer therapeutics

H Sun, S Burrola, J Wu, WQ Ding - International journal of molecular …, 2020 - mdpi.com
Extracellular vesicles (EVs) are small lipid bilayer-delimited nanoparticles released from all
types of cells examined thus far. Several groups of EVs, including exosomes, microvesicles …

Extracellular vesicles in cancer diagnostics and therapeutics

A Shehzad, SU Islam, R Shahzad, S Khan… - Pharmacology & …, 2021 - Elsevier
Cancer promotion, development, and malignant transformation is greatly influenced by cell-
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …

Probing the mechanisms of extracellular vesicle biogenesis and function in cancer

A Latifkar, RA Cerione… - Biochemical Society …, 2018 - portlandpress.com
Tumor cells interact with each other, and their surroundings, using a variety of mechanisms
to promote virtually all aspects of cancer progression. One such form of intercellular …